{"id":"W3138552287","doi":"10.3390/v13030455","title":"Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut","year":2021,"lang":"en","type":"article","venue":"Viruses","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Prophage; Microbiology; Biology; Lytic cycle; Antibiotics; Lysogenic cycle; Bacteriophage; Bacteria; Microbiome; Bacteroides fragilis; Antimicrobial; Virology; Virus; Genetics; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002242267,0.0004589053,0.0004886073,0.0003205616,0.0002544706,0.000297609,0.0000840397,0.0003645532,0.002467541],"category_scores_gemma":[0.0004708623,0.0001750108,0.0003707081,0.0003412715,0.0002126573,0.0001602572,0.0003720185,0.0004811688,0.0003077844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009630938,"about_ca_system_score_gemma":0.0001781797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004166069,"about_ca_topic_score_gemma":0.0008294702,"domain_scores_codex":[0.9995796,0.0001008217,0.00004065453,0.00007379439,0.0001357913,0.00006932698],"domain_scores_gemma":[0.9995394,0.0001742434,0.0001232383,0.00003721452,0.00006771533,0.00005835205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003963727,0.00008634722,0.004075143,0.0001699447,0.00001999994,0.0001508153,0.00007799267,0.00003477897,0.9895258,0.00001491187,0.00004784171,0.005400049],"study_design_scores_gemma":[0.00003919187,0.006590236,0.1221959,0.00007560715,0.00009082416,0.001023407,0.0004465758,0.0002061737,0.8668537,0.00005896422,0.002402408,0.00001698508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943675,0.003103151,0.0004914415,0.00007812787,0.00003591824,0.00005050437,0.0003055876,0.00001918929,0.001548458],"genre_scores_gemma":[0.9939346,0.001970581,0.001789779,0.0001271805,0.00003127491,0.00004921294,0.0004349205,0.00001045577,0.001652074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002467541,"threshold_uncertainty_score":0.008254766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03373428834537683,"score_gpt":0.3005747815298323,"score_spread":0.2668404931844555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}