{"id":"W3138552287","doi":"10.3390/v13030455","title":"Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut","year":2021,"lang":"en","type":"article","venue":"Viruses","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Prophage; Microbiology; Biology; Lytic cycle; Antibiotics; Lysogenic cycle; Bacteriophage; Bacteria; Microbiome; Bacteroides fragilis; Antimicrobial; Virology; Virus; Genetics; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00006318599,0.00007700721,0.00008780554,0.00001594027,0.0001739319,0.00007138892,0.0001553965,0.00004443685,0.007595815],"category_scores_gemma":[0.00002627423,0.00005920923,0.00002672562,0.0001943522,0.00007032893,0.0002465081,0.0001565881,0.0001333611,0.0009134777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007839785,"about_ca_system_score_gemma":0.00001198391,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01007965,"about_ca_topic_score_gemma":0.02593661,"domain_scores_codex":[0.9993728,0.00007642149,0.0001628652,0.000193331,0.00006466268,0.000129959],"domain_scores_gemma":[0.9996522,0.00004025738,0.00003862718,0.0002236872,0.000005649693,0.00003957651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000005796795,0.00007675385,0.005533356,5.09795e-7,0.000006232607,0.000003194104,0.000518688,0.00001010603,0.9867031,0.00001776258,0.004086795,0.003037719],"study_design_scores_gemma":[0.000176761,0.00002965254,0.6882014,0.00002362536,0.00001524225,0.000006049525,0.0002646474,0.000007551122,0.1993446,0.0001197798,0.1116954,0.0001152961],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968229,0.00002188028,0.00002309583,0.001793979,0.0003958473,0.0001261961,0.00005010851,0.00002343209,0.0007425813],"genre_scores_gemma":[0.9977297,0.00001140818,0.0003023344,0.001350113,0.000141198,0.00002476934,0.00004739214,0.000008980188,0.0003841525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7873585,"threshold_uncertainty_score":0.9998644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03373428834537683,"score_gpt":0.3005747815298323,"score_spread":0.2668404931844555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}