{"id":"W3138923170","doi":"10.1186/s13063-021-05147-2","title":"Prophylactic Antibiotic Regimens In Tumor Surgery (PARITY): a multi-center randomized controlled study comparing alternative antibiotic regimens in patients undergoing tumor resections with endoprosthetic replacements—a statistical analysis plan","year":2021,"lang":"en","type":"article","venue":"Trials","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; Juravinski Cancer Centre; Juravinski Hospital; Impact; McMaster University","funders":"Institute of Cancer Research; Physicians' Services Incorporated Foundation; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Orthopedic Research and Education Foundation; McMaster University; Vanderbilt University Medical Center; Orthopaedic Research and Education Foundation; Vanderbilt University; Canadian Orthopaedic Foundation","keywords":"Medicine; Surgery; Randomized controlled trial; Regimen; Orthopedic surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004311751,0.0004831452,0.006150721,0.001222622,0.000130087,0.0001312116,0.00009294089,0.00005822154,0.00007504133],"category_scores_gemma":[0.007239428,0.0003342052,0.0005277705,0.001336803,0.0001425023,0.00011282,0.00008012498,0.000354096,0.00001561117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000537827,"about_ca_system_score_gemma":0.0003694766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000966406,"about_ca_topic_score_gemma":0.00316887,"domain_scores_codex":[0.9913186,0.003876553,0.002418488,0.001004926,0.0007603038,0.0006211067],"domain_scores_gemma":[0.9894722,0.008323176,0.001045329,0.0006713371,0.0002817162,0.0002062171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1502073,0.02198548,0.8193466,0.00009887332,0.004505008,0.003201222,0.0004212589,0.0001357316,0.00002056724,0.00003845389,0.0000152881,0.0000242081],"study_design_scores_gemma":[0.5484397,0.0008548311,0.442912,0.0005423306,0.00458424,0.00003919479,0.0007000205,0.001250812,0.0004214577,0.00001303215,7.599251e-7,0.0002415532],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892625,0.0002295237,0.0001687942,0.0001410709,0.0002084559,0.009780308,0.00004473092,0.00004473051,0.000119912],"genre_scores_gemma":[0.9983243,0.00003346754,0.0008065511,0.00008885998,0.00004236332,0.0003489152,0.0001987588,0.000048094,0.000108628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3982325,"threshold_uncertainty_score":0.999911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08976451872563082,"score_gpt":0.3538801926290936,"score_spread":0.2641156739034628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}