{"id":"W3138937819","doi":"10.3389/fncel.2021.658990","title":"Endogenous Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Plays a Protective Effect Against Noise-Induced Hearing Loss","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fondation de l'Avenir pour la Recherche Médicale Appliquée","keywords":"Vasoactive intestinal peptide; Spiral ganglion; Pituitary adenylate cyclase-activating peptide; Receptor; Internal medicine; Neuropeptide; Endocrinology; Endogeny; Adenylyl cyclase; Knockout mouse; Biology; Transgene; Organ of Corti; Adenylate kinase; Cell biology; Chemistry; Cochlea; Neuroscience; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001537004,0.0006133561,0.0004087661,0.0004494158,0.0001886769,0.0003936367,0.0003034834,0.0003472912,0.001229409],"category_scores_gemma":[0.0001613507,0.000168079,0.0003179408,0.0001512902,0.0004500989,0.0004092082,0.0003263779,0.000662628,0.0002661785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001843933,"about_ca_system_score_gemma":0.0002378874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004856819,"about_ca_topic_score_gemma":0.0005373235,"domain_scores_codex":[0.9997918,0.00001541967,0.00002051771,0.00005389157,0.00006762103,0.00005083405],"domain_scores_gemma":[0.999846,0.00001303477,0.00004920181,0.00001793191,0.0000189012,0.00005490178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009660805,0.00001112254,0.0001889563,0.00004461523,0.000003953096,0.00009190025,0.00001292149,0.00001891202,0.9980372,0.00006256238,0.0000301015,0.001401196],"study_design_scores_gemma":[0.00003486716,0.0008047645,0.02795409,0.00002645972,0.00009578979,0.001347598,0.0001303833,0.00058221,0.965353,0.0001902279,0.003461126,0.00001966676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869469,0.006525557,0.003855966,0.0002822363,0.00008494522,0.00002289551,0.0003371735,0.0002918106,0.001652477],"genre_scores_gemma":[0.9901707,0.004735578,0.002259555,0.0001199388,0.00005096455,0.00004344653,0.0003452488,0.00004204786,0.002232449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001229409,"threshold_uncertainty_score":0.00411278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04198576353425947,"score_gpt":0.2438515246963423,"score_spread":0.2018657611620828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}