{"id":"W3139008901","doi":"","title":"Membrane binding of the main component of lipofuscin, A2E, and its photo-irradiated product","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Lipofuscin; Component (thermodynamics); Irradiation; Product (mathematics); Membrane; Chemistry; Biophysics; Biochemistry; Physics; Mathematics; Biology; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897395,0.0003120423,0.0001955432,0.000208546,0.0003469931,0.000344233,0.0002784644,0.0005501833,0.004314571],"category_scores_gemma":[0.0003829041,0.0001164054,0.0002793116,0.0001789196,0.0001893829,0.0003278274,0.0003097742,0.0005821818,0.001002554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005539089,"about_ca_system_score_gemma":0.0002733255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0021064,"about_ca_topic_score_gemma":0.0008809008,"domain_scores_codex":[0.9997988,0.00005067081,0.000005753877,0.00004002401,0.00003323941,0.00007147297],"domain_scores_gemma":[0.9998201,0.00007678579,0.0000169761,0.00001943225,0.00003251585,0.00003427595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002735902,0.00002759863,0.0002177041,0.00003023853,0.0000113963,0.00007750207,0.00003334791,0.00004990151,0.9980957,0.0002508236,0.00007253596,0.0008596358],"study_design_scores_gemma":[0.0000177834,0.0003481128,0.006629895,0.000009979872,0.00001025137,0.0002845881,0.0001074716,0.001358182,0.988641,0.0001402281,0.002444412,0.000008063616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921247,0.001337649,0.002386403,0.0001129781,0.00003316628,0.0000234041,0.0001146162,0.00002339308,0.003843679],"genre_scores_gemma":[0.9919732,0.0004478043,0.001055841,0.00006018129,0.00001321868,0.00001827369,0.0005359204,0.00001222572,0.005883302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004314571,"threshold_uncertainty_score":0.01443368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0242856525217812,"score_gpt":0.2767690356982846,"score_spread":0.2524833831765034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}