{"id":"W3139036521","doi":"10.1016/j.jtho.2021.01.085","title":"FP03.03 Clinical Activity of BMS-986012, an Anti–Fucosyl-GM1 Monoclonal Antibody, Plus Nivolumab in Small Cell Lung Cancer","year":2021,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Medicine; Nivolumab; Regimen; Oncology; Lung cancer; Chemotherapy; Internal medicine; Monoclonal antibody; Stage (stratigraphy); Cisplatin; Cancer; Antibody; Immunotherapy; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003279583,0.0005113464,0.0009882372,0.0003232294,0.0002398094,0.000640072,0.0004801109,0.0006754529,0.003175261],"category_scores_gemma":[0.0002653446,0.0001993201,0.0007002525,0.000243311,0.0002764274,0.0003427715,0.0001499606,0.001730171,0.0008855302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006264129,"about_ca_system_score_gemma":0.000977267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002216806,"about_ca_topic_score_gemma":0.003984162,"domain_scores_codex":[0.9998436,0.00002623595,0.00001046678,0.00002023395,0.00002638756,0.00007307076],"domain_scores_gemma":[0.999899,0.00001369582,0.000009726865,0.000007570278,0.00001106988,0.00005887168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1828381,0.02268316,0.004654749,0.0009506792,0.0009470768,0.0008451231,0.0002155442,0.004159033,0.3571361,0.0009331578,0.01255559,0.4120817],"study_design_scores_gemma":[0.07836611,0.5408426,0.08485474,0.0002096354,0.002318693,0.003508227,0.0002760516,0.01185063,0.23916,0.000634721,0.03782053,0.0001580455],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885573,0.003354235,0.0003028396,0.0003556743,0.0002756542,0.0002303696,0.0005905689,0.0002248988,0.006108513],"genre_scores_gemma":[0.993856,0.001054025,0.0004293324,0.0002696265,0.00008249417,0.0001203123,0.001027201,0.00001860517,0.003142368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003175261,"threshold_uncertainty_score":0.01062232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04313495739633973,"score_gpt":0.477689935984453,"score_spread":0.4345549785881133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}