{"id":"W3139457007","doi":"10.1186/s12929-020-00706-2","title":"The ESCRT-III molecules regulate the apical targeting of bile salt export pump","year":2021,"lang":"en","type":"article","venue":"Journal of Biomedical Science","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Taiwan University; National Science Council; University of British Columbia; Ministry of Science and Technology, Taiwan; Academia Sinica; Johns Hopkins University","keywords":"Bile Salt Export Pump; Endosome; Cholestasis; Cell biology; Transport protein; Biology; Biochemistry; Secretion; Golgi apparatus; Chemistry; Transporter; Endoplasmic reticulum; Endocrinology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007000442,0.0002073763,0.0001229535,0.000162385,0.000169365,0.0003134541,0.0001277407,0.0002190545,0.001335978],"category_scores_gemma":[0.00008427612,0.00008709085,0.0002178944,0.0000921442,0.0001661699,0.0002387435,0.0002214459,0.0003262031,0.0006339605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003867578,"about_ca_system_score_gemma":0.000122203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000533163,"about_ca_topic_score_gemma":0.0005423111,"domain_scores_codex":[0.9999352,0.000007763219,0.000005074815,0.00001374155,0.0000163441,0.00002194369],"domain_scores_gemma":[0.9999387,0.000004775214,0.00001964406,0.000003788603,0.00001872788,0.00001432853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007406874,0.000008308349,0.0007905063,0.00003077678,0.000004787766,0.00012617,0.00001136152,0.00004834107,0.9977273,0.0001892568,0.00009652686,0.00089261],"study_design_scores_gemma":[0.00001920186,0.0001048024,0.05219764,0.00001938891,0.00003228781,0.0004882361,0.0001125056,0.002545779,0.937317,0.0002180279,0.006935513,0.000009563593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894444,0.003240302,0.004153444,0.0001332308,0.00002960386,0.00002415077,0.0004507283,0.00008772111,0.002436319],"genre_scores_gemma":[0.9939485,0.0009608211,0.00120895,0.00005883279,0.000007425478,0.00001700657,0.000567821,0.00001848049,0.003212166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001335978,"threshold_uncertainty_score":0.004469275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008816158333570884,"score_gpt":0.2617107991682902,"score_spread":0.2528946408347192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}