{"id":"W3139496681","doi":"10.1101/2021.03.15.434853","title":"Vtc5 is localized to the vacuole membrane by the conserved AP-3 complex to regulate polyphosphate synthesis in budding yeast","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Ottawa","keywords":"Vacuole; Cell biology; Saccharomyces cerevisiae; Biology; Yeast; Biochemistry; Polyphosphate; Phosphate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008956371,0.0003995904,0.0002180736,0.0002547831,0.0002906953,0.0006310218,0.0003599642,0.0003515153,0.0007988034],"category_scores_gemma":[0.0001076541,0.0002023001,0.000346473,0.0001882504,0.0002243128,0.0002131408,0.0004536799,0.0004593469,0.0006568751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008005816,"about_ca_system_score_gemma":0.0002386744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001621818,"about_ca_topic_score_gemma":0.001424019,"domain_scores_codex":[0.9998744,0.0000116989,0.00001716603,0.00004108158,0.00003419067,0.0000214626],"domain_scores_gemma":[0.9998782,0.00001475591,0.00003825188,0.0000151524,0.00001828741,0.00003540991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005941592,0.000006134424,0.0003232667,0.00002219008,0.000003411785,0.0001237613,0.00001602371,0.00005983694,0.9986745,0.0002023389,0.00005399181,0.0004551108],"study_design_scores_gemma":[0.0000208191,0.00004372079,0.01270503,0.00001908545,0.00002004194,0.0005826227,0.0001173722,0.004028736,0.9774843,0.0001977823,0.004766079,0.00001446007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984295,0.002959365,0.009929272,0.0001810601,0.00007409333,0.00002866185,0.001108956,0.0002021569,0.001221461],"genre_scores_gemma":[0.9932827,0.0004875837,0.002644819,0.00006865512,0.00000502015,0.00001679444,0.001325018,0.00006011214,0.002109311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001621818,"threshold_uncertainty_score":0.005808651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317566685134692,"score_gpt":0.2454097822035934,"score_spread":0.2222341153522465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}