{"id":"W3139514317","doi":"10.1093/cvr/cvab098","title":"Understanding the role of<i>Iroquoi</i>s homeobox transcription factor 5 (<i>IRX5</i>) in cardiac function: getting to the (human) heart of the matter","year":2021,"lang":"en","type":"letter","venue":"Cardiovascular Research","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University; University Health Network; University of Ottawa","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Homeobox; Homeobox protein Nkx-2.5; Transcription factor; Cardiac function curve; Internal medicine; Endocrinology; Biology; Medicine; Genetics; Heart failure; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002727181,0.0006138002,0.001248726,0.0004485548,0.002335094,0.002384664,0.001360203,0.03171102,0.004372332],"category_scores_gemma":[0.01181145,0.0004883948,0.0008916737,0.000334169,0.002615236,0.002709555,0.001098033,0.03202746,0.004961682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003338392,"about_ca_system_score_gemma":0.002418325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003282802,"about_ca_topic_score_gemma":0.00465198,"domain_scores_codex":[0.9985268,0.0004102447,0.0001869848,0.0002199191,0.0004527564,0.0002032097],"domain_scores_gemma":[0.9945191,0.00315584,0.000312196,0.0001924349,0.0009452958,0.0008752826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001169523,0.00005700867,0.0003916436,0.00005551287,0.00001418549,0.001541142,0.0000818183,0.00006599053,0.0004321193,0.003564155,0.9807137,0.01296574],"study_design_scores_gemma":[0.0002280044,0.0001397835,0.001271383,0.000203871,0.00003984767,0.001997888,0.0003537777,0.0006404379,0.0007239661,0.02681855,0.9675201,0.00006247171],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002892308,0.001608738,0.0001115412,0.9703509,0.02623556,0.000004816922,0.00002851662,0.00001924137,0.001351502],"genre_scores_gemma":[0.004594043,0.002900848,0.0002621,0.9015139,0.08397724,0.0000233829,0.00003190137,0.00001858726,0.006677927],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03171102,"threshold_uncertainty_score":0.0242219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0800853476709216,"score_gpt":0.301296648387375,"score_spread":0.2212113007164534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}