{"id":"W3139688759","doi":"10.1016/j.toxrep.2021.03.025","title":"In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxypropionaldehyde (reuterin) produced by Lactobacillus reuteri","year":2021,"lang":"en","type":"article","venue":"Toxicology Reports","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; International Development Research Centre","keywords":"Hemolysis; Toxicity; Lactobacillus reuteri; Chemistry; In vivo; Cytotoxicity; Gastrointestinal tract; Lactate dehydrogenase; Preservative; In vitro; Microbiology; Antimicrobial; Pharmacology; Biochemistry; Biology; Food science; Lactobacillus; Fermentation; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002603748,0.0004158427,0.0002971315,0.0002528196,0.0001418275,0.0002986143,0.0001830267,0.0003338859,0.0004838281],"category_scores_gemma":[0.0002784387,0.0001109176,0.0003249305,0.0002529715,0.0001764331,0.0002905251,0.0002021641,0.0003879925,0.0001501886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001587526,"about_ca_system_score_gemma":0.0001353839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007018068,"about_ca_topic_score_gemma":0.0006119693,"domain_scores_codex":[0.9998178,0.00004218763,0.00002399429,0.00003622059,0.00005369566,0.00002617794],"domain_scores_gemma":[0.9997591,0.00007442229,0.00007676515,0.00002322569,0.00004749382,0.00001887675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001879649,0.00004936008,0.000346436,0.00008472227,0.000009097857,0.00007841622,0.00003474767,0.0001362128,0.9978033,0.0000212404,0.00001813831,0.00123053],"study_design_scores_gemma":[0.000009611848,0.00116158,0.0051905,0.00001560112,0.00003900168,0.0001551049,0.00005951851,0.0006762961,0.9917252,0.00002289493,0.0009368266,0.000007923732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932434,0.003749076,0.001412104,0.0000611662,0.00002103108,0.00003296005,0.0003207953,0.00001844468,0.001140967],"genre_scores_gemma":[0.9927508,0.002934813,0.00226094,0.00004835826,0.00001549303,0.00003791262,0.0005362303,0.00001243951,0.001402999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007018068,"threshold_uncertainty_score":0.001618624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0195601717837386,"score_gpt":0.2205659536262279,"score_spread":0.2010057818424894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}