{"id":"W3139688759","doi":"10.1016/j.toxrep.2021.03.025","title":"In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxypropionaldehyde (reuterin) produced by Lactobacillus reuteri","year":2021,"lang":"en","type":"article","venue":"Toxicology Reports","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; International Development Research Centre","keywords":"Hemolysis; Toxicity; Lactobacillus reuteri; Chemistry; In vivo; Cytotoxicity; Gastrointestinal tract; Lactate dehydrogenase; Preservative; In vitro; Microbiology; Antimicrobial; Pharmacology; Biochemistry; Biology; Food science; Lactobacillus; Fermentation; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003366365,0.00009278586,0.0002492118,0.00001040453,0.00002614713,0.000005782629,0.00005187538,0.00007492364,0.0001025374],"category_scores_gemma":[0.0001924676,0.00004713091,0.00003525902,0.0001820091,0.0001721388,0.00006816551,0.000100164,0.00009486947,1.786143e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002503693,"about_ca_system_score_gemma":0.00003672489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004140504,"about_ca_topic_score_gemma":0.00007755099,"domain_scores_codex":[0.9988602,0.0001066507,0.0004502688,0.0003163243,0.0001046824,0.0001619069],"domain_scores_gemma":[0.99941,0.00006983936,0.0002615506,0.00008836656,0.0001082717,0.00006195538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005393529,0.0001425966,0.07241842,0.00002409581,0.000004908482,0.00005218696,0.00003130427,2.372354e-7,0.9266935,0.00001839333,0.000033826,0.0005266047],"study_design_scores_gemma":[0.00007776669,0.0002511984,0.1901493,0.00001617448,0.000004406353,0.0002162173,0.00002591026,0.00000807075,0.8085987,0.0005388847,0.00005469307,0.00005860882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983477,0.00007802015,0.000002453939,0.001218926,0.00005894388,0.0001608656,0.00004236004,0.000009989052,0.00008073408],"genre_scores_gemma":[0.9993064,0.000008064423,0.0004619364,0.0001129065,0.00001773157,0.000006867027,0.00005849523,6.735195e-7,0.00002691503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1180948,"threshold_uncertainty_score":0.1921943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0195601717837386,"score_gpt":0.2205659536262279,"score_spread":0.2010057818424894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}