{"id":"W3139852843","doi":"10.1093/jnci/93.1.67","title":"RESPONSE: Re: Promoter Methylation and Silencing of the Retinoic Acid Receptor-  Gene in Lung Carcinomas","year":2001,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Gene silencing; Cancer research; Methylation; Retinoic acid receptor; Retinoic acid; Gene; Biology; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002313048,0.0004340678,0.0003962551,0.000650121,0.0003508929,0.0003737302,0.0003485561,0.0006354859,0.02270643],"category_scores_gemma":[0.0003154754,0.0002138986,0.0002603242,0.000162037,0.0002706443,0.0002352794,0.0003789145,0.0008554995,0.004777813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005380138,"about_ca_system_score_gemma":0.0002295351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009384906,"about_ca_topic_score_gemma":0.001758935,"domain_scores_codex":[0.9997566,0.00004735558,0.00001816807,0.00006240798,0.00005439719,0.00006108766],"domain_scores_gemma":[0.9998274,0.00004205287,0.00002874744,0.00002911351,0.0000230302,0.0000497207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008130211,0.0000846813,0.001907595,0.0001367405,0.00002939481,0.0005320197,0.00005075641,0.0001789577,0.982091,0.0007704239,0.004080459,0.009324961],"study_design_scores_gemma":[0.0001517602,0.0003762228,0.04186543,0.00002828204,0.00005397179,0.003297901,0.0002104082,0.001115936,0.9282795,0.0005252394,0.02408054,0.0000148426],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9261535,0.01132447,0.009156589,0.005007029,0.0008580599,0.0002150223,0.005086361,0.00159415,0.04060471],"genre_scores_gemma":[0.9327601,0.001247779,0.001648028,0.0005805156,0.0001856758,0.0001170759,0.002774391,0.0001211626,0.06056534],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02270643,"threshold_uncertainty_score":0.07596052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207840060092218,"score_gpt":0.2935535902042569,"score_spread":0.2714751896033347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}