{"id":"W3141356097","doi":"10.1016/j.leukres.2021.106576","title":"Isatuximab plus pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma according to prior lines of treatment and refractory status: ICARIA-MM subgroup analysis","year":2021,"lang":"en","type":"article","venue":"Leukemia Research","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Sanofi","keywords":"Pomalidomide; Dexamethasone; Lenalidomide; Refractory (planetary science); Medicine; Internal medicine; Multiple myeloma; Oncology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001747179,0.000881329,0.002731585,0.0007368564,0.0002830029,0.001009563,0.0005557212,0.000737941,0.002191697],"category_scores_gemma":[0.001711731,0.0003401868,0.005917985,0.0007862494,0.0002448115,0.0004052215,0.0005426896,0.0009934925,0.0002719219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006583325,"about_ca_system_score_gemma":0.0008350608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001801749,"about_ca_topic_score_gemma":0.005374209,"domain_scores_codex":[0.999082,0.0003601309,0.0001453259,0.0001514279,0.00008256369,0.0001786212],"domain_scores_gemma":[0.9991977,0.0002401334,0.0001745477,0.0001403181,0.00006202668,0.0001853886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6983964,0.001607505,0.1902066,0.001009147,0.04150492,0.0006032728,0.0003000145,0.002353234,0.01143248,0.0001935708,0.003246487,0.04914631],"study_design_scores_gemma":[0.1825224,0.07660039,0.6391928,0.0003314645,0.07408616,0.00185299,0.001019553,0.009680999,0.003791435,0.001707254,0.009004616,0.0002099511],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942808,0.00324975,0.0001610912,0.0001757819,0.00005752156,0.0002634515,0.0009515714,0.00001677234,0.0008433302],"genre_scores_gemma":[0.9966819,0.0004686563,0.0002264474,0.0001989826,0.00008632292,0.0002119312,0.001677354,0.000008347924,0.0004401189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002731585,"threshold_uncertainty_score":0.009240031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04205705449643045,"score_gpt":0.3424922657441016,"score_spread":0.3004352112476712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}