{"id":"W3141368659","doi":"10.3174/ajnr.a7097","title":"Imaging Patterns Characterizing Mitochondrial Leukodystrophies","year":2021,"lang":"en","type":"article","venue":"American Journal of Neuroradiology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Association Européenne contre les Leucodystrophies; ZonMw; Ionis Pharmaceuticals; Biogen; Eli Lilly and Company","keywords":"Hyperintensity; Leukodystrophy; Corpus callosum; Pathology; Medicine; White matter; Globus pallidus; Magnetic resonance imaging; Neuroscience; Biology; Basal ganglia; Disease; Radiology; Central nervous system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002055651,0.0003537635,0.0002006071,0.001256617,0.0002483182,0.0002812873,0.0002301167,0.0003791656,0.001699922],"category_scores_gemma":[0.000981012,0.0001963157,0.0001820004,0.0006037988,0.0004976725,0.0002868314,0.0003571279,0.0002100985,0.0002207282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002073929,"about_ca_system_score_gemma":0.0001706551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112239,"about_ca_topic_score_gemma":0.001522701,"domain_scores_codex":[0.9998703,0.00001447878,0.00002573483,0.00003171972,0.00002600486,0.00003169589],"domain_scores_gemma":[0.9992133,0.00009612841,0.0004888785,0.00003819787,0.00005458948,0.0001088646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007235138,0.00007363649,0.9136662,0.0001334189,0.00009315211,0.01884881,0.0004877016,0.0003052028,0.05410521,0.000158092,0.0003838754,0.01102115],"study_design_scores_gemma":[0.00005059293,0.0002346857,0.9110596,0.00002655084,0.00006267361,0.08212411,0.0003453827,0.0003697741,0.005252802,0.0001511894,0.0003122651,0.00001053732],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990453,0.0001898391,0.0002067274,0.00002506558,0.000001389559,0.000009856329,0.00006131258,0.00000956061,0.0004507655],"genre_scores_gemma":[0.9995345,0.0000729427,0.0002044379,0.00001671572,0.000005796643,0.000004075687,0.0001050684,0.000002719574,0.0000536805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001699922,"threshold_uncertainty_score":0.00568682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00877877283072854,"score_gpt":0.2390675691444271,"score_spread":0.2302887963136986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}