{"id":"W3141928157","doi":"10.1172/jci.insight.147190","title":"Hypoxia and viral infectious diseases","year":2021,"lang":"en","type":"review","venue":"JCI Insight","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; University of Toronto","keywords":"Immune system; Mediator; Hypoxia (environmental); Hypoxia-inducible factors; Viral replication; Oxygen tension; Biology; Pathogen; Disease; Immunology; Cell biology; Virus; Medicine; Oxygen; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004469772,0.0003710364,0.0009419785,0.00007329752,0.00008218565,0.00006772573,0.0001409007,0.000392303,0.00004374925],"category_scores_gemma":[0.00008262494,0.0003144313,0.0004172268,0.000117269,0.00008444579,0.000003719203,0.0002267809,0.0001807771,0.00001800452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001890644,"about_ca_system_score_gemma":0.000355499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001298728,"about_ca_topic_score_gemma":0.00002291896,"domain_scores_codex":[0.9986537,0.0001139285,0.0002935696,0.0005721512,0.0001165868,0.0002501143],"domain_scores_gemma":[0.9991446,0.00001764855,0.0001449147,0.000476331,0.00005707431,0.0001594252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003685576,0.00006629709,0.000007237759,0.001854284,0.0002331547,0.000009818198,0.00001288586,1.574639e-7,0.0001693785,0.000180375,0.01599684,0.9814659],"study_design_scores_gemma":[0.0002334249,0.00006193499,0.00001738254,0.0005957294,0.0006178766,0.00009861527,0.000002766902,1.51601e-7,0.00004144461,0.00001843896,0.9979311,0.000381097],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001560527,0.9948994,0.00001936756,0.000006664427,0.001889196,0.0002743056,0.0001243437,0.00002185996,0.002608791],"genre_scores_gemma":[0.00005323829,0.9923148,0.00002842673,0.0001594792,0.004166714,0.00009459149,0.0007173795,0.00006030751,0.002405102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9819343,"threshold_uncertainty_score":0.9999308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01563838452818643,"score_gpt":0.284668985597432,"score_spread":0.2690306010692455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}