{"id":"W3141928157","doi":"10.1172/jci.insight.147190","title":"Hypoxia and viral infectious diseases","year":2021,"lang":"en","type":"review","venue":"JCI Insight","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; University of Toronto","keywords":"Immune system; Mediator; Hypoxia (environmental); Hypoxia-inducible factors; Viral replication; Oxygen tension; Biology; Pathogen; Disease; Immunology; Cell biology; Virus; Medicine; Oxygen; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000489053,0.0008043369,0.0009303449,0.001848892,0.0003448174,0.001306275,0.0008285437,0.001594181,0.004135727],"category_scores_gemma":[0.0007104059,0.0002584442,0.0003355489,0.001629514,0.0006553867,0.001585698,0.0009051317,0.002350215,0.003068158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001082829,"about_ca_system_score_gemma":0.001173994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001312936,"about_ca_topic_score_gemma":0.002501863,"domain_scores_codex":[0.9998347,0.00002844253,0.00002045513,0.00002797533,0.00006534333,0.0000231308],"domain_scores_gemma":[0.9997088,0.0001005463,0.00003873736,0.00001086129,0.0000854805,0.00005558202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005445779,0.00003691295,0.0001611149,0.006449012,0.00005284048,0.0002588379,0.00005947585,0.0002103089,0.001184202,0.006909117,0.09852637,0.8860973],"study_design_scores_gemma":[0.000005770232,0.00002689301,0.0003924018,0.001354903,0.0000207977,0.0008961379,0.00002801224,0.00003286433,0.0001431946,0.001777748,0.9953126,0.000008692987],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003200109,0.9980283,0.00005573111,0.0004381159,0.0005085763,0.000001944689,0.000007187248,0.000005419573,0.0009227628],"genre_scores_gemma":[0.000317659,0.9977337,0.00008638165,0.0004050716,0.0006059457,0.000003443466,0.00002287177,0.000001481697,0.0008234301],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004135727,"threshold_uncertainty_score":0.01383537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01563838452818643,"score_gpt":0.284668985597432,"score_spread":0.2690306010692455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}