{"id":"W3142080073","doi":"10.1038/s41392-021-00507-5","title":"Pyroptosis: mechanisms and diseases","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2308,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"Project 211; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Pyroptosis; Medicine; Immunology; Inflammasome; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003603555,0.0008001621,0.001076653,0.00160326,0.0003480001,0.001212541,0.0006323424,0.001039722,0.003610127],"category_scores_gemma":[0.0004206576,0.0002070746,0.0004513765,0.001188923,0.0005929936,0.001248325,0.0007408367,0.001618302,0.001792019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005798286,"about_ca_system_score_gemma":0.0009374768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000490812,"about_ca_topic_score_gemma":0.000606998,"domain_scores_codex":[0.999835,0.00002802239,0.00002569341,0.00003044703,0.00005953491,0.00002121797],"domain_scores_gemma":[0.9998595,0.00005120304,0.00002411886,0.000006724825,0.00003504076,0.00002348838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001186865,0.0000795643,0.0002889472,0.01768448,0.00009428682,0.0005756412,0.0001029119,0.0004095125,0.004209635,0.009518056,0.04683241,0.9200858],"study_design_scores_gemma":[0.00001502654,0.00007297454,0.0005541917,0.002537933,0.00004893857,0.003104825,0.00005304952,0.00007484264,0.0006220964,0.005426407,0.9874747,0.00001492175],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001126843,0.9982181,0.0001136069,0.0002549634,0.0002395434,0.000004174771,0.00001494352,0.000007978515,0.001033976],"genre_scores_gemma":[0.0009641442,0.9976134,0.0001319846,0.0002287166,0.0002590493,0.00000694806,0.00002952738,0.000001310216,0.0007649736],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003610127,"threshold_uncertainty_score":0.01207709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01677021942760649,"score_gpt":0.2687090103631539,"score_spread":0.2519387909355474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}