{"id":"W3142306462","doi":"10.1128/mbio.00130-21","title":"Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation","year":2021,"lang":"en","type":"article","venue":"mBio","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Bacterial adhesin; Biofilm; Lectin; Microbiology; Chemistry; Ligand (biochemistry); Biology; Cell biology; Bacteria; Biochemistry; Computational biology; Escherichia coli; Receptor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007553809,0.000176852,0.000142812,0.00008602567,0.0002626324,0.000244298,0.0003252761,0.0002766214,0.0009969486],"category_scores_gemma":[0.00009242069,0.00009816004,0.0001385303,0.00007835431,0.000185919,0.0001528492,0.0001417599,0.0003976084,0.0002954536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003128973,"about_ca_system_score_gemma":0.0003130767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001037377,"about_ca_topic_score_gemma":0.00108871,"domain_scores_codex":[0.9999485,0.000007894788,0.000002415843,0.000009504279,0.00001661447,0.00001513168],"domain_scores_gemma":[0.9999589,0.000005382437,0.000006852239,0.000003032846,0.000008930308,0.00001692568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009078738,0.0000432744,0.0006480203,0.00003836749,0.000007068435,0.0002519807,0.00002513189,0.0005966246,0.9940739,0.002128038,0.0002002034,0.001896589],"study_design_scores_gemma":[0.00009635671,0.0005961864,0.02042075,0.00002079492,0.0000356182,0.001634321,0.0001930748,0.04327955,0.9227469,0.002904222,0.008023686,0.00004849553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892643,0.0007542447,0.005846391,0.000328907,0.00004398503,0.00002071954,0.0001078264,0.00007623851,0.003557357],"genre_scores_gemma":[0.9968335,0.0002426553,0.001955261,0.00007352284,0.000004940048,0.000005734284,0.0001308677,0.000005835706,0.0007477262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001037377,"threshold_uncertainty_score":0.003335118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009486648548135182,"score_gpt":0.2171404508151838,"score_spread":0.2076538022670487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}