{"id":"W3142405888","doi":"10.1161/circresaha.120.317791","title":"Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin","year":2021,"lang":"en","type":"article","venue":"Circulation Research","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Optech (Canada)","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Pathological; Fibrosis; Cardiac fibrosis; Medicine; Ventricular remodeling; Salinomycin; Pathology; Internal medicine; Bioinformatics; Heart failure; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000168264,0.0004231647,0.0002982355,0.0002800037,0.0001269154,0.0002399459,0.0001825493,0.0002407445,0.0009865955],"category_scores_gemma":[0.0001107184,0.0000792997,0.0002370293,0.0001605154,0.0001772594,0.0001281256,0.0001428961,0.0004387069,0.000220318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001897645,"about_ca_system_score_gemma":0.0002456084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003134763,"about_ca_topic_score_gemma":0.0008541633,"domain_scores_codex":[0.9999326,0.00001118815,0.000007993133,0.00001347029,0.0000204537,0.00001419085],"domain_scores_gemma":[0.9999051,0.00001649853,0.0000375388,0.000007237121,0.000008550238,0.00002502613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003363283,0.0001378438,0.0003884214,0.0001108318,0.00001550161,0.00007356633,0.000006119928,0.0001653827,0.9913549,0.00008103479,0.0001162069,0.007213899],"study_design_scores_gemma":[0.0001986931,0.002590382,0.007002721,0.00001688226,0.00004744927,0.0004296805,0.00001093881,0.0005754036,0.9847381,0.00004457034,0.004338516,0.000006601159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787568,0.01167356,0.005691402,0.0003835042,0.00005701648,0.000200649,0.0008086167,0.0001679463,0.002260411],"genre_scores_gemma":[0.9861637,0.006132851,0.005427382,0.0001489689,0.00003649727,0.00009057765,0.0007633839,0.00001436096,0.001222284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009865955,"threshold_uncertainty_score":0.003300548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1072105451356948,"score_gpt":0.4100956834611842,"score_spread":0.3028851383254895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}