{"id":"W3142818195","doi":"10.3390/cancers13071660","title":"Malignant Pleural Mesothelioma Interactome with 364 Novel Protein-Protein Interactions","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute for Occupational Safety and Health; National Institute of Mental Health; Centers for Disease Control and Prevention; National Institutes of Health; York University; Indian Institute of Science; University of Pittsburgh; NYU Langone Medical Center; Roswell Park Cancer Institute","keywords":"Interactome; Mesothelioma; Drug repositioning; Gene; Computational biology; Biology; Cancer research; Bioinformatics; Medicine; Drug; Pathology; Genetics; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001712402,0.0004428449,0.0005884245,0.00119478,0.0005133709,0.0004452216,0.0001923707,0.0004393956,0.001896247],"category_scores_gemma":[0.000657948,0.0001320181,0.000956915,0.001701682,0.0001848586,0.0002751322,0.0004930981,0.0002803975,0.000348587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003383147,"about_ca_system_score_gemma":0.0004371587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002082787,"about_ca_topic_score_gemma":0.003784728,"domain_scores_codex":[0.9996607,0.00003716122,0.00002553846,0.0001121383,0.000106878,0.00005760458],"domain_scores_gemma":[0.9996592,0.0001457823,0.00008816762,0.00002413547,0.00003671491,0.00004601091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004570943,0.0005220467,0.6161063,0.002342068,0.001400046,0.007034292,0.0004041255,0.0102176,0.2927026,0.001042374,0.009459186,0.05419835],"study_design_scores_gemma":[0.0001022045,0.0003287283,0.9521136,0.00005602013,0.0005366029,0.004029987,0.0001734525,0.01425836,0.01567101,0.0007475751,0.01194154,0.00004097856],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.968649,0.001803777,0.001152595,0.0001506389,0.00001038269,0.00003657907,0.02694765,0.0001639872,0.001085451],"genre_scores_gemma":[0.9079068,0.0007320991,0.003547993,0.0001568617,0.00002818137,0.0001316175,0.08658548,0.00002933794,0.0008815906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002082787,"threshold_uncertainty_score":0.006343544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01828889013646845,"score_gpt":0.273486520601635,"score_spread":0.2551976304651666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}