{"id":"W3142818195","doi":"10.3390/cancers13071660","title":"Malignant Pleural Mesothelioma Interactome with 364 Novel Protein-Protein Interactions","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute for Occupational Safety and Health; National Institute of Mental Health; Centers for Disease Control and Prevention; National Institutes of Health; York University; Indian Institute of Science; University of Pittsburgh; NYU Langone Medical Center; Roswell Park Cancer Institute","keywords":"Interactome; Mesothelioma; Drug repositioning; Gene; Computational biology; Biology; Cancer research; Bioinformatics; Medicine; Drug; Pathology; Genetics; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00001708159,0.000119169,0.0001413187,0.00004636466,0.00005716476,0.00001764573,0.00004270689,0.00002158615,0.001533644],"category_scores_gemma":[0.00002109902,0.00009068403,0.00006648825,0.0001449313,0.00006817109,0.0001155104,0.0000304918,0.0001074431,0.00009078077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006955878,"about_ca_system_score_gemma":0.0003490084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001458823,"about_ca_topic_score_gemma":0.00006541239,"domain_scores_codex":[0.9992671,0.00001060565,0.0001288176,0.0002278488,0.000204217,0.0001613852],"domain_scores_gemma":[0.9995721,0.0000115219,0.0000485044,0.0001818833,0.00004212195,0.0001438686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001429397,0.0002432265,0.01839456,0.0001800766,0.0002736853,0.0003566512,0.0001981852,0.0002797579,0.9747776,0.0005718019,0.0009034153,0.00239169],"study_design_scores_gemma":[0.00570041,0.001019647,0.3298788,0.002921311,0.0003671597,0.0007803063,0.00169769,0.0008996698,0.5649227,0.0001882967,0.09084615,0.000777762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994722,0.0002023735,0.0003058056,0.001052381,0.0001058584,0.0003084003,0.00008776313,0.000040797,0.003174608],"genre_scores_gemma":[0.9878569,0.000005776913,0.0009918328,0.0006329056,0.0001386336,0.0001407727,0.0001018464,0.00002158528,0.01010973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4098548,"threshold_uncertainty_score":0.9993791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01828889013646845,"score_gpt":0.273486520601635,"score_spread":0.2551976304651666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}