{"id":"W3142875742","doi":"10.33137/jns.v2i1.34611","title":"In Vitro Treg Immunosuppression Assay of GITR Proteins Could Elucidate the Autoimmune-mediated Mechanism Underlying Type 1 Narcolepsy","year":2021,"lang":"en","type":"article","venue":"UTSC s Journal of Natural Sciences","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"University of Toronto Scarborough","keywords":"Narcolepsy; Immunology; Immune system; Biology; Population; IL-2 receptor; Mechanism (biology); Cerebrospinal fluid; Neuroscience; Medicine; Cell biology; T cell; Neurology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002227932,0.0001430188,0.0002995043,0.0002952216,0.0003928278,0.0001631557,0.001137328,0.00008811428,0.0001271231],"category_scores_gemma":[0.003540564,0.000079839,0.0001219268,0.002232381,0.0005069631,0.000736366,0.0002170721,0.0008306234,0.000008666352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006411152,"about_ca_system_score_gemma":0.0005376295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006252697,"about_ca_topic_score_gemma":0.00001283795,"domain_scores_codex":[0.9965338,0.000738073,0.0005545616,0.000270504,0.001471492,0.0004315831],"domain_scores_gemma":[0.997951,0.001010528,0.0004460109,0.0002111662,0.0003089887,0.00007231063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001459893,0.0000845704,0.00005665837,0.000008915251,0.000007036525,0.0001455281,0.0002912229,0.00005766798,0.9924997,0.0006408241,0.00006212005,0.005999772],"study_design_scores_gemma":[0.0005465162,0.0001937195,0.002032617,0.0001360636,0.000007574406,0.0002120292,0.0005781929,0.002742943,0.99017,0.00275769,0.0005115755,0.000111081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912397,0.002036108,0.00009370907,0.004691912,0.001285434,0.0002115673,0.000005899228,0.00000999609,0.0004257174],"genre_scores_gemma":[0.9988919,0.0002310581,0.0002917333,0.0002837284,0.00004657782,0.000003483289,6.867966e-7,0.000007653521,0.0002431102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007652312,"threshold_uncertainty_score":0.4238642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0678980859600782,"score_gpt":0.3512749637321924,"score_spread":0.2833768777721142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}