{"id":"W3142875742","doi":"10.33137/jns.v2i1.34611","title":"In Vitro Treg Immunosuppression Assay of GITR Proteins Could Elucidate the Autoimmune-mediated Mechanism Underlying Type 1 Narcolepsy","year":2021,"lang":"en","type":"article","venue":"UTSC s Journal of Natural Sciences","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"University of Toronto Scarborough","keywords":"Narcolepsy; Immunology; Immune system; Biology; Population; IL-2 receptor; Mechanism (biology); Cerebrospinal fluid; Neuroscience; Medicine; Cell biology; T cell; Neurology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003304824,0.0003700127,0.0001791166,0.0001708236,0.0001013159,0.0001512319,0.0001233393,0.0002108963,0.001203457],"category_scores_gemma":[0.0001350311,0.00007462843,0.0002196168,0.00009560335,0.0001202437,0.00008404492,0.0001192961,0.000519118,0.0002275451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007892679,"about_ca_system_score_gemma":0.00009640807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000169228,"about_ca_topic_score_gemma":0.0003202091,"domain_scores_codex":[0.9998285,0.00006471705,0.00001649601,0.00002848298,0.00002993318,0.00003193273],"domain_scores_gemma":[0.9999021,0.00003372457,0.00001661515,0.000015045,0.00001392299,0.00001858424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302676,0.000106379,0.0004089592,0.00003284728,0.00000352673,0.00002577406,0.0000211775,0.00003629702,0.998482,0.00003429507,0.00001674998,0.0007017969],"study_design_scores_gemma":[0.00005578631,0.00368804,0.005779567,0.00001356236,0.00004562661,0.0002645931,0.00004134572,0.001157892,0.9877387,0.00006414056,0.001147365,0.000003381777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938442,0.0009168148,0.003657044,0.00002937842,0.00005169702,0.0000713444,0.0001050071,0.00004495805,0.001279693],"genre_scores_gemma":[0.9945982,0.0004734156,0.00287718,0.00006251816,0.00003341783,0.0001100909,0.0003407535,0.000008414652,0.001495911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001203457,"threshold_uncertainty_score":0.004025936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0678980859600782,"score_gpt":0.3512749637321924,"score_spread":0.2833768777721142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}