{"id":"W3142959462","doi":"10.1016/s2352-3018(20)30340-4","title":"Long-acting cabotegravir plus rilpivirine for treatment in adults with HIV-1 infection: 96-week results of the randomised, open-label, phase 3 FLAIR study","year":2021,"lang":"en","type":"article","venue":"The Lancet HIV","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":false,"ca_institutions":"GlaxoSmithKline (Canada); St. Michael's Hospital","funders":"Janssen Research and Development; Barts Charity; ViiV Healthcare; Janssen Pharmaceuticals; Gilead Sciences","keywords":"Rilpivirine; Medicine; Dolutegravir; Abacavir; Emtricitabine; Regimen; Lamivudine; Internal medicine; Viral load; Human immunodeficiency virus (HIV); Antiretroviral therapy; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00412976,0.002194853,0.003852125,0.0004356177,0.0005764134,0.001541194,0.001452464,0.003123994,0.009581384],"category_scores_gemma":[0.004291664,0.001007991,0.00337182,0.0004540274,0.001609175,0.002817308,0.0007454054,0.004923279,0.001973912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009145483,"about_ca_system_score_gemma":0.0009783747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001847691,"about_ca_topic_score_gemma":0.002524298,"domain_scores_codex":[0.9981172,0.001187119,0.00009785083,0.0002246494,0.0001304084,0.0002428217],"domain_scores_gemma":[0.9975533,0.0008683438,0.0005169368,0.0003066015,0.0001297083,0.0006251479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9791722,0.004294879,0.0003174654,0.0003680619,0.0006908672,0.00002095521,0.00007360249,0.0002238104,0.001794504,0.00005913647,0.0006688667,0.01231557],"study_design_scores_gemma":[0.9521493,0.04358042,0.002440445,0.00004464719,0.0004563472,0.0000329873,0.00004807884,0.000215885,0.0002916142,0.0001491262,0.0005541499,0.00003687747],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853942,0.004400173,0.001065238,0.0009675913,0.0004763185,0.002074148,0.003358052,0.0002154765,0.002048783],"genre_scores_gemma":[0.9786743,0.002892008,0.003501967,0.001592918,0.0005578184,0.004206067,0.002835574,0.0001154901,0.00562379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009581384,"threshold_uncertainty_score":0.03205293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07966455498937293,"score_gpt":0.393228581801075,"score_spread":0.313564026811702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}