{"id":"W3143332846","doi":"10.7554/elife.66190","title":"Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Yale University; National Institutes of Health; Junta de Andalucía; Cincinnati Children's Hospital Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Centro Nacional de Investigaciones Cardiovasculares","keywords":"Myeloid; Progenitor cell; Inflammation; Bone marrow; CCL19; Immunology; Cell biology; Biology; Systemic inflammation; Lymphatic system; Macrophage; Cancer research; Stem cell; Chemokine; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001620841,0.0003021553,0.0002036878,0.0002239613,0.000153666,0.000320382,0.0001184653,0.0002186376,0.001638389],"category_scores_gemma":[0.00009668232,0.00009801039,0.0001615837,0.0001255577,0.0001943558,0.0003144176,0.0004635146,0.0007817723,0.000632711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002174034,"about_ca_system_score_gemma":0.0002405926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001908388,"about_ca_topic_score_gemma":0.0003066694,"domain_scores_codex":[0.9998724,0.00002199912,0.000006384561,0.00003065846,0.0000259852,0.00004246597],"domain_scores_gemma":[0.9999402,0.000006363705,0.00001664482,0.000007635222,0.000006346595,0.00002282406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002185568,0.00001547154,0.0006954204,0.00006939883,0.000004061581,0.0002713079,0.00003185277,0.00006382445,0.9940404,0.0005573586,0.0001561237,0.003876275],"study_design_scores_gemma":[0.0000522258,0.0005331677,0.02023177,0.00003998247,0.00002285806,0.001852319,0.0002161498,0.0009995941,0.9544652,0.0006595418,0.02091775,0.000009429326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706593,0.008556296,0.01459986,0.0004347592,0.00008022387,0.0001076773,0.0007649058,0.0002128355,0.004584242],"genre_scores_gemma":[0.986995,0.002406794,0.005288586,0.0001923592,0.00003377248,0.00007272926,0.0006922612,0.00003349362,0.004284982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001638389,"threshold_uncertainty_score":0.005480945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01674593933830483,"score_gpt":0.2432887060902702,"score_spread":0.2265427667519654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}