{"id":"W3143509230","doi":"10.1097/der.0000000000000725","title":"Patient-Reported Symptoms and Disease Impacts in Adults With Moderate-to-Severe Atopic Dermatitis: Results From a Phase 2b Study With Abrocitinib","year":2021,"lang":"en","type":"article","venue":"Dermatitis","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Medicine; Atopic dermatitis; Eczema Area and Severity Index; Dermatology Life Quality Index; Quality of life (healthcare); Placebo; Hospital Anxiety and Depression Scale; Depression (economics); Rating scale; Severity of illness; Internal medicine; Dermatology; Anxiety; Physical therapy; Disease; Psychiatry; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004626693,0.0003386585,0.000595091,0.0001642889,0.0001305351,0.00008415368,0.00007038649,0.00008736749,0.0001036978],"category_scores_gemma":[0.0003928261,0.0002724141,0.00004651358,0.0004076956,0.00009679506,0.0003129408,0.00006895852,0.0002216421,0.00002183203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005196266,"about_ca_system_score_gemma":0.0004668933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003365113,"about_ca_topic_score_gemma":0.001174097,"domain_scores_codex":[0.9977013,0.00017354,0.0006437483,0.000629694,0.0004355716,0.0004161383],"domain_scores_gemma":[0.9979465,0.0001516507,0.0001830249,0.0005983603,0.0002322726,0.0008882176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004202561,0.002951753,0.904455,0.0003428617,0.0005276538,0.06000746,0.01154261,0.00006431682,0.000007752309,0.00001172949,0.01195302,0.003933283],"study_design_scores_gemma":[0.03468702,0.0006202518,0.9561939,0.002090217,0.0003445008,0.001453327,0.002774188,0.0006135356,0.0002268745,0.0001122144,0.0004899445,0.0003940845],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932868,0.0008117585,0.00007748362,0.002982123,0.00005252974,0.001274668,0.0006776408,0.0001076958,0.0007292231],"genre_scores_gemma":[0.9916065,0.00005858293,0.0003572583,0.006665724,0.0000334499,0.0001851525,0.0009987766,0.00003866349,0.0000558688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05855413,"threshold_uncertainty_score":0.9999728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008395401942535881,"score_gpt":0.2564923092461179,"score_spread":0.2480969073035821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}