{"id":"W3143638314","doi":"10.1002/1878-0261.12954","title":"The evolutionarily conserved long non‐coding RNA <i>LINC00261</i> drives neuroendocrine prostate cancer proliferation and metastasis <i>via</i> distinct nuclear and cytoplasmic mechanisms","year":2021,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Cancer Research UK","keywords":"Downregulation and upregulation; Biology; Gene knockdown; Cancer research; Metastasis; Prostate cancer; Long non-coding RNA; Cell biology; Gene; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008416161,0.0001529432,0.0001404049,0.0001227456,0.0001944542,0.000406808,0.00009525691,0.0001406572,0.001335669],"category_scores_gemma":[0.0001368961,0.00007639943,0.0001672288,0.0001607833,0.0001918986,0.0001120744,0.0002200377,0.0003002137,0.0003160652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001893504,"about_ca_system_score_gemma":0.0002237161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007849861,"about_ca_topic_score_gemma":0.001797571,"domain_scores_codex":[0.9998937,0.0000107106,0.000008546554,0.00002878298,0.00003852037,0.00001969607],"domain_scores_gemma":[0.9999083,0.0000129189,0.00003467897,0.000006620719,0.00001163255,0.00002570476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000058267,0.00001033248,0.002444101,0.00003392366,0.000005846964,0.0001004954,0.00001328506,0.00005963551,0.9952756,0.0001185459,0.0001342903,0.001745625],"study_design_scores_gemma":[0.00003512117,0.0005737903,0.2632917,0.00003168063,0.00007783944,0.001535165,0.0002424076,0.005211333,0.7165164,0.0002617801,0.01219667,0.00002616406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992134,0.00112338,0.002237911,0.0001387662,0.00002803549,0.00001725636,0.0006773114,0.0001455606,0.003497752],"genre_scores_gemma":[0.9962122,0.0004164319,0.0006836142,0.000130916,0.00001097692,0.00001564244,0.0008237653,0.00001977645,0.001686756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001335669,"threshold_uncertainty_score":0.004468322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007789157163422103,"score_gpt":0.2651227144043928,"score_spread":0.2573335572409707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}