{"id":"W314365644","doi":"10.1016/j.colsurfb.2015.05.015","title":"Polymeric micelles based on poly(ethylene oxide) and α-carbon substituted poly(ɛ-caprolactone): An in vitro study on the effect of core forming block on polymeric micellar stability, biocompatibility, and immunogenicity","year":2015,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Micelle; Polymer chemistry; Chemistry; Polymerization; Ethylene oxide; Caprolactone; Amphiphile; Copolymer; Sodium dodecyl sulfate; Dynamic light scattering; Polymer; Chemical engineering; Organic chemistry; Aqueous solution; Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005961484,0.0004349708,0.0002422643,0.0002031188,0.0001191089,0.0002257286,0.000196099,0.0003343398,0.0003978416],"category_scores_gemma":[0.0004018898,0.0002350116,0.0003082287,0.0001236894,0.0002202302,0.0003650706,0.0001316097,0.0003643244,0.0001762166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002287283,"about_ca_system_score_gemma":0.0002284677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004341419,"about_ca_topic_score_gemma":0.0004899215,"domain_scores_codex":[0.999823,0.00004710005,0.00001740003,0.00003254275,0.00003615128,0.00004380881],"domain_scores_gemma":[0.9997517,0.00009117124,0.00006235747,0.00001286027,0.00004173053,0.0000402214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002012707,0.00003671198,0.00004650043,0.00002220443,0.000004428764,0.00001893158,0.0000108797,0.00004334697,0.9991693,0.00002994433,0.000005877099,0.0004105628],"study_design_scores_gemma":[0.00002332063,0.0006464156,0.0004023744,0.000002519486,0.00001986526,0.00005091437,0.000004140546,0.0002946249,0.998246,0.00001027133,0.0002971728,0.000002480501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946929,0.001913141,0.002690055,0.00003661951,0.00003581573,0.00005259287,0.0000616603,0.00003313311,0.0004841815],"genre_scores_gemma":[0.9941564,0.001012718,0.003244859,0.00005143654,0.00002041556,0.0000393578,0.0001795966,0.00001736021,0.001277952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005961484,"threshold_uncertainty_score":0.003152788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02640057875804782,"score_gpt":0.2646532356852024,"score_spread":0.2382526569271546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}