{"id":"W314365644","doi":"10.1016/j.colsurfb.2015.05.015","title":"Polymeric micelles based on poly(ethylene oxide) and α-carbon substituted poly(ɛ-caprolactone): An in vitro study on the effect of core forming block on polymeric micellar stability, biocompatibility, and immunogenicity","year":2015,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Micelle; Polymer chemistry; Chemistry; Polymerization; Ethylene oxide; Caprolactone; Amphiphile; Copolymer; Sodium dodecyl sulfate; Dynamic light scattering; Polymer; Chemical engineering; Organic chemistry; Aqueous solution; Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008581665,0.0004398112,0.0005333126,0.0001443163,0.0001204524,0.0000764721,0.0002775252,0.0001471737,0.000002618527],"category_scores_gemma":[0.0000922415,0.0003036869,0.00007384807,0.0002142834,0.0003727282,0.00001571841,0.0001910699,0.0001962385,6.962721e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002837521,"about_ca_system_score_gemma":0.00006191482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001804148,"about_ca_topic_score_gemma":0.0004683714,"domain_scores_codex":[0.9977529,0.0004380223,0.0004472977,0.0007608027,0.0002579351,0.0003430169],"domain_scores_gemma":[0.9987878,0.0002235639,0.0001887386,0.0005834358,0.00006050608,0.0001559074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004735466,0.0003528525,0.134977,0.00003993802,0.00006669028,0.000002710392,0.0003793521,0.00002787351,0.858153,5.618716e-7,0.000003169104,0.001261466],"study_design_scores_gemma":[0.0020485,0.009102652,0.02395676,0.00007951417,0.00004911813,0.000004368338,0.001967188,0.002754357,0.9597105,0.000004337976,0.000009444766,0.0003132142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897072,0.009022264,0.000003919299,0.00009787852,0.00009721993,0.0009041036,0.00006146492,0.00001438587,0.00009155928],"genre_scores_gemma":[0.9996358,0.0001450384,0.0000406095,0.00006974883,0.00001920885,0.0000244399,0.00002048861,0.00002527193,0.00001943362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1110202,"threshold_uncertainty_score":0.9999415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02640057875804782,"score_gpt":0.2646532356852024,"score_spread":0.2382526569271546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}