{"id":"W3143815372","doi":"10.21203/rs.3.rs-339282/v1","title":"Global and temporal state of the human gut microbiome in health and disease","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kootenay Association for Science & Technology","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Medical Research Council; Science for Life Laboratory; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; King's College London; National Research Foundation of Korea; Wellcome Trust; Agence Nationale de la Recherche; Ministry of Science and ICT, South Korea; Knut och Alice Wallenbergs Stiftelse; Uppsala Multidisciplinary Center for Advanced Computational Science; National Research Foundation; European Commission; Directorate for Biological Sciences; Israel Institute for Biological Research; National Institute for Health and Care Research","keywords":"Microbiome; Disease; State (computer science); Gut microbiome; Human health; Biology; Computational biology; Evolutionary biology; Political science; Data science; Medicine; Computer science; Environmental health; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005047998,0.0001624561,0.0002812527,0.001078711,0.0002713338,0.0008888914,0.00009236502,0.0002728673,0.001307252],"category_scores_gemma":[0.001016965,0.00009988953,0.0002294358,0.001463932,0.0004275004,0.0003124418,0.00064828,0.0001924201,0.0002227941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001598295,"about_ca_system_score_gemma":0.0001989007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002926477,"about_ca_topic_score_gemma":0.002475605,"domain_scores_codex":[0.9997541,0.00007108387,0.00001496691,0.00007869423,0.00003708125,0.00004405099],"domain_scores_gemma":[0.9995222,0.0001138939,0.0001743513,0.00006571074,0.0000682528,0.00005565842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000560885,0.00002835073,0.9453381,0.0001353807,0.0001703136,0.0001995879,0.001021625,0.0006794552,0.03100275,0.0003274521,0.0002840251,0.02025211],"study_design_scores_gemma":[0.000001540768,0.00004721214,0.9968111,0.00001468844,0.00003583714,0.0002278374,0.0005991478,0.0001919883,0.001116621,0.0003226915,0.0006252985,0.000006061063],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966536,0.001485563,0.0004901197,0.00003890145,0.00000605247,0.00000243674,0.0007400858,0.000007187623,0.0005761076],"genre_scores_gemma":[0.99845,0.000407111,0.0004605036,0.00001322949,0.000006435797,0.000003318322,0.0004231053,0.000004507451,0.0002316993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002926477,"threshold_uncertainty_score":0.005818844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03541467906795096,"score_gpt":0.4046333604806356,"score_spread":0.3692186814126847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}