{"id":"W3143815372","doi":"10.21203/rs.3.rs-339282/v1","title":"Global and temporal state of the human gut microbiome in health and disease","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kootenay Association for Science & Technology","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Medical Research Council; Science for Life Laboratory; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; King's College London; National Research Foundation of Korea; Wellcome Trust; Agence Nationale de la Recherche; Ministry of Science and ICT, South Korea; Knut och Alice Wallenbergs Stiftelse; Uppsala Multidisciplinary Center for Advanced Computational Science; National Research Foundation; European Commission; Directorate for Biological Sciences; Israel Institute for Biological Research; National Institute for Health and Care Research","keywords":"Microbiome; Disease; State (computer science); Gut microbiome; Human health; Biology; Computational biology; Evolutionary biology; Political science; Data science; Medicine; Computer science; Environmental health; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007443257,0.0001487571,0.0002427541,0.00007207449,0.0001409422,0.00005804779,0.0002244432,0.0001356019,0.000005270071],"category_scores_gemma":[0.0001123541,0.0001218843,0.00006447516,0.000167267,0.0003108524,0.000001845875,0.001783809,0.0003816324,2.893148e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008276543,"about_ca_system_score_gemma":0.001913153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001899523,"about_ca_topic_score_gemma":0.00254968,"domain_scores_codex":[0.9980289,0.0005588824,0.000297533,0.0005189865,0.0001854908,0.000410214],"domain_scores_gemma":[0.9988744,0.00001009914,0.0001004327,0.0005285472,0.000151222,0.0003352876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001780153,0.0003042936,0.7761306,0.01046837,0.00006034813,0.00002845317,0.0006540213,0.00002641172,0.205642,0.0001269627,0.004085497,0.002294945],"study_design_scores_gemma":[0.0007478878,0.0002717332,0.9896021,0.001436649,0.000004273622,0.00001027095,0.0004200999,0.00001302214,0.00114887,0.0009344706,0.005182505,0.0002281441],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825585,0.01453862,0.000006454532,0.001647198,0.00004644979,0.0006294512,0.0005343193,0.000002724222,0.00003621416],"genre_scores_gemma":[0.9965758,0.00244496,0.00008187393,0.0001378681,0.00004094281,0.00001764325,0.000460403,0.00001353575,0.0002269498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2134714,"threshold_uncertainty_score":0.4970297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03541467906795096,"score_gpt":0.4046333604806356,"score_spread":0.3692186814126847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}