{"id":"W3143907823","doi":"10.1126/scitranslmed.abf1906","title":"The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates","year":2021,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":497,"is_retracted":false,"has_abstract":true,"ca_institutions":"AbCellera (Canada)","funders":"Defense Sciences Office, DARPA; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust; G. Harold and Leila Y. Mathers Charitable Foundation; Eli Lilly and Company; U.S. Department of Energy","keywords":"Virology; Antibody; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Neutralizing antibody; Immunology; Coronavirus disease 2019 (COVID-19); Sars virus; Medicine; 2019-20 coronavirus outbreak; Biology; Outbreak; Pathology; Infectious disease (medical specialty); Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003650946,0.0004476298,0.0003520006,0.0004216939,0.0002521603,0.000399627,0.0003192489,0.0005359652,0.002431599],"category_scores_gemma":[0.0002499805,0.0002067658,0.0002099712,0.0001554127,0.0003580799,0.0002866788,0.000112208,0.0008863173,0.0008322698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002984807,"about_ca_system_score_gemma":0.0006152599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001931617,"about_ca_topic_score_gemma":0.003932048,"domain_scores_codex":[0.9997755,0.00005745257,0.00001293363,0.00004054865,0.00006240827,0.00005112005],"domain_scores_gemma":[0.9998766,0.00001365255,0.00002845009,0.00002014549,0.00002711917,0.00003396248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007864481,0.0006397981,0.0005708582,0.00007731216,0.00002717782,0.00005517258,0.0000487765,0.000118027,0.9811782,0.0002153561,0.0007148492,0.01556797],"study_design_scores_gemma":[0.000776568,0.02782123,0.02324321,0.00006695424,0.0000798731,0.001440211,0.00009092612,0.001951846,0.9133966,0.0003540224,0.03075624,0.00002230056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726534,0.005462185,0.007629763,0.0006596561,0.0002953909,0.0005045053,0.001184298,0.0006473199,0.01096347],"genre_scores_gemma":[0.9801059,0.002147778,0.005341483,0.0002989705,0.00008571296,0.0001735263,0.001731318,0.00004848878,0.01006669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431599,"threshold_uncertainty_score":0.008134544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06535195160773641,"score_gpt":0.408656778167771,"score_spread":0.3433048265600346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}