{"id":"W3143907823","doi":"10.1126/scitranslmed.abf1906","title":"The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates","year":2021,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":497,"is_retracted":false,"has_abstract":true,"ca_institutions":"AbCellera (Canada)","funders":"Defense Sciences Office, DARPA; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust; G. Harold and Leila Y. Mathers Charitable Foundation; Eli Lilly and Company; U.S. Department of Energy","keywords":"Virology; Antibody; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Neutralizing antibody; Immunology; Coronavirus disease 2019 (COVID-19); Sars virus; Medicine; 2019-20 coronavirus outbreak; Biology; Outbreak; Pathology; Infectious disease (medical specialty); Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00195652,0.0001906975,0.0002914344,0.0004312192,0.0005557364,0.00007740097,0.0002537447,0.00006901271,0.000009468444],"category_scores_gemma":[0.0007543819,0.0001279331,0.00007296553,0.002547128,0.001380827,0.0003720517,0.00004068646,0.0004593708,0.00002681988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001473708,"about_ca_system_score_gemma":0.001309999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003868218,"about_ca_topic_score_gemma":0.0008600574,"domain_scores_codex":[0.9968363,0.00008734134,0.0004617172,0.0005360192,0.001483667,0.0005949668],"domain_scores_gemma":[0.9987579,0.0002901465,0.00007554974,0.0003559382,0.0004645461,0.00005590261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008202619,0.00008624694,0.07675797,0.00009761925,0.00001105687,0.00007471818,0.0006092073,0.000007077473,0.9130577,0.001929263,0.00003475197,0.007252375],"study_design_scores_gemma":[0.00239582,0.000207565,0.3169414,0.0005742554,0.00001978039,0.00009877605,0.0001332905,0.003115247,0.6582488,0.00234048,0.01573564,0.000188902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771422,0.0008369623,0.0005305709,0.01061278,0.0003077498,0.0006862462,0.000001955619,0.00006844978,0.009813085],"genre_scores_gemma":[0.9875717,0.00006374705,0.0002323412,0.01175355,0.0002785899,0.00005219244,0.00001226419,0.00001714386,0.00001851957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2548088,"threshold_uncertainty_score":0.5216962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06535195160773641,"score_gpt":0.408656778167771,"score_spread":0.3433048265600346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}