{"id":"W3145035817","doi":"","title":"Decrease of liposomal size and retarding effect on fluconazole skin permeation by lysine derivatives","year":2011,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Permeation; Liposome; Chemistry; Vesicle; Transdermal; Chromatography; Drug carrier; Drug delivery; Fluconazole; Particle size; Membrane; Organic chemistry; Biochemistry; Pharmacology; Antifungal","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001645473,0.0002478969,0.0001668514,0.00009560453,0.00008641728,0.0001915737,0.0001367513,0.0002344975,0.0008423313],"category_scores_gemma":[0.0003367068,0.0001288039,0.0001502356,0.00007618533,0.0002038687,0.0002708799,0.0001223568,0.0002184411,0.000212851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002138843,"about_ca_system_score_gemma":0.0001441787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003992536,"about_ca_topic_score_gemma":0.0004920083,"domain_scores_codex":[0.9998835,0.0000271744,0.0000136393,0.00002043183,0.00002840743,0.00002693815],"domain_scores_gemma":[0.9998294,0.0000502028,0.00005439665,0.0000160003,0.000028881,0.00002121973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007133177,0.000006128222,0.00004614697,0.00001699547,0.000001763636,0.00001648786,0.000007566168,0.00003096347,0.9992065,0.00002285386,0.000007272407,0.000565969],"study_design_scores_gemma":[0.000005432905,0.0001241779,0.0006538315,0.000001499803,0.000005063705,0.00003562689,0.00000443912,0.0001346482,0.9987237,0.000004558076,0.0003051446,0.000001728842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971516,0.0009474189,0.001140937,0.00005147808,0.000007396061,0.00001341798,0.00006334424,0.00003298476,0.0005914888],"genre_scores_gemma":[0.9976735,0.0004507142,0.001080061,0.00003111512,0.000003352152,0.00001306118,0.00007237733,0.00001328853,0.0006626106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008423313,"threshold_uncertainty_score":0.002817869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1234775622576311,"score_gpt":0.4513712100284965,"score_spread":0.3278936477708653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}