{"id":"W3145049629","doi":"10.3390/cells10040824","title":"Neurological Disorders Associated with WWOX Germline Mutations—A Comprehensive Overview","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"H2020 European Research Council; European Research Council","keywords":"WWOX; Spinocerebellar ataxia; Phenotype; Genetics; Biology; Allele; Population; Germline; Medicine; Bioinformatics; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000528826,0.0004634905,0.0008499043,0.00005114775,0.00009190392,0.00004093167,0.0002748595,0.0003606324,0.00007973407],"category_scores_gemma":[0.00004054549,0.0003744195,0.0003525258,0.0002579257,0.0001102687,0.000001471724,0.0002152636,0.0002513538,0.00003716239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001216798,"about_ca_system_score_gemma":0.0002416194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002001423,"about_ca_topic_score_gemma":0.00002408329,"domain_scores_codex":[0.99814,0.0002472086,0.0003813219,0.0007216232,0.0001789486,0.0003309291],"domain_scores_gemma":[0.9991173,0.00005653966,0.0002390988,0.0003888092,0.00009310648,0.0001052016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002859938,0.0009348161,0.00006176442,0.005144679,0.001466653,0.0001512834,0.00003342497,0.0001963389,0.002126453,0.00004401613,0.01284874,0.9769632],"study_design_scores_gemma":[0.000280333,0.0002543997,0.0002109662,0.000743892,0.0002885101,0.00001635766,0.000008210537,0.000003486465,0.0000721434,0.000006931239,0.9976494,0.0004653942],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002059096,0.9966824,0.00003171251,0.00002353959,0.0002046675,0.0005153083,0.0001028349,0.00001678535,0.0003636214],"genre_scores_gemma":[0.0002905467,0.9950059,0.0001633456,0.0003748995,0.00002606653,0.00007156392,0.003340684,0.00007788144,0.0006491283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9848006,"threshold_uncertainty_score":0.9998708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03546384970270798,"score_gpt":0.2918416388697783,"score_spread":0.2563777891670703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}