{"id":"W3145650647","doi":"10.1093/noajnl/vdab024.001","title":"BIMG-02. IMAGING IMMORTALITY: TERT EXPRESSION ALTERS GLUCOSE METABOLISM IN LOW-GRADE GLIOMAS IN A MANNER THAT CAN BE LEVERAGED FOR NONINVASIVE METABOLIC IMAGING","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Pentose phosphate pathway; Neurosphere; Glucose Transporter Type 1; Glutathione; Chemistry; GLUT1; Metabolism; Cancer research; Biology; Biochemistry; Enzyme; Glucose uptake; Endocrinology; Glycolysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003093353,0.0003418178,0.0005655368,0.0002502407,0.0001261344,0.00003384355,0.0002514034,0.0001863722,0.00003814004],"category_scores_gemma":[0.0004814795,0.0003373716,0.0001886845,0.0002926569,0.0001720395,0.00004380539,0.0001895971,0.000321842,0.000002495399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003825651,"about_ca_system_score_gemma":0.0002502901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005336332,"about_ca_topic_score_gemma":0.001303143,"domain_scores_codex":[0.9971325,0.0006159698,0.0004776067,0.001001252,0.0001491376,0.0006235099],"domain_scores_gemma":[0.9989241,0.0001952534,0.0002083341,0.0004490977,0.00009830909,0.0001249474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003310864,0.0001642318,0.01900149,0.00003560178,0.00001957793,0.000659937,0.0003047711,0.0002415984,0.9742665,0.0001039837,0.0003333165,0.004537875],"study_design_scores_gemma":[0.002837809,0.00006574324,0.003310881,0.00003040808,0.00003658076,0.0002879641,0.0006005257,0.0001030293,0.8062983,0.0003033917,0.185821,0.0003044163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974826,0.01653239,0.001675566,0.003042532,0.002869144,0.000618462,0.00008939183,0.00003229234,0.0003142461],"genre_scores_gemma":[0.9852107,0.002644965,0.002616572,0.008067447,0.0005118236,0.0004153498,0.0003340039,0.00006143066,0.0001377367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1854877,"threshold_uncertainty_score":0.9999079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703742037941136,"score_gpt":0.2887955741815896,"score_spread":0.2717581538021782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}