{"id":"W3145650647","doi":"10.1093/noajnl/vdab024.001","title":"BIMG-02. IMAGING IMMORTALITY: TERT EXPRESSION ALTERS GLUCOSE METABOLISM IN LOW-GRADE GLIOMAS IN A MANNER THAT CAN BE LEVERAGED FOR NONINVASIVE METABOLIC IMAGING","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Pentose phosphate pathway; Neurosphere; Glucose Transporter Type 1; Glutathione; Chemistry; GLUT1; Metabolism; Cancer research; Biology; Biochemistry; Enzyme; Glucose uptake; Endocrinology; Glycolysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215546,0.0003856937,0.000294292,0.0002920589,0.0001883702,0.0003097674,0.0002547882,0.0003670811,0.003116522],"category_scores_gemma":[0.000104258,0.0001714137,0.0001854894,0.0003091175,0.0002528698,0.0001803553,0.0001780926,0.0007046245,0.0008205766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002960765,"about_ca_system_score_gemma":0.0003054759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001440737,"about_ca_topic_score_gemma":0.001653725,"domain_scores_codex":[0.9998203,0.00002531164,0.00001403143,0.00004074468,0.00005671125,0.00004286955],"domain_scores_gemma":[0.9999003,0.00001023823,0.00003072128,0.00001172301,0.00001319408,0.00003369044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001133414,0.00003862081,0.0001052683,0.00002063308,0.000003667132,0.00002840882,0.000005929176,0.00003034599,0.9984212,0.00006323447,0.0001480212,0.001021355],"study_design_scores_gemma":[0.00002474793,0.0003387555,0.002411407,0.000003155926,0.00001335753,0.0002505313,0.00001875075,0.000658369,0.9935766,0.00004454215,0.002655846,0.000003995198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854476,0.0009941302,0.005635285,0.0003219616,0.00009876613,0.00009240054,0.002693699,0.0005718236,0.004144426],"genre_scores_gemma":[0.9768207,0.0008447919,0.008631352,0.0002739574,0.00001527636,0.0002372491,0.003944959,0.000132401,0.009099297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003116522,"threshold_uncertainty_score":0.01042581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703742037941136,"score_gpt":0.2887955741815896,"score_spread":0.2717581538021782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}