{"id":"W3145881487","doi":"10.4049/jimmunol.2001253","title":"OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Key Technology Research and Development Program of Shandong; National Natural Science Foundation of China","keywords":"Deubiquitinating enzyme; Innate immune system; Biology; Cell biology; Ubiquitin; Signal transducing adaptor protein; Proinflammatory cytokine; Regulator; Immunity; Signal transduction; Innate lymphoid cell; Immunology; Inflammation; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001099878,0.000312112,0.0001971168,0.0002540929,0.0002329232,0.0003403385,0.0001737377,0.0002008469,0.0009541806],"category_scores_gemma":[0.00009200942,0.0001062659,0.0001831869,0.0001267647,0.0002477957,0.0002009607,0.0002776259,0.0003288604,0.0002178689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003458358,"about_ca_system_score_gemma":0.0001003979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002447888,"about_ca_topic_score_gemma":0.000406463,"domain_scores_codex":[0.999889,0.0000145173,0.00001166681,0.00003059745,0.00002064314,0.00003352269],"domain_scores_gemma":[0.9998705,0.00001266941,0.00006494817,0.000009743988,0.000009762794,0.00003234096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001564237,0.00001590511,0.001821871,0.00003356321,0.00000414895,0.0001287924,0.00001067646,0.00009211491,0.9963353,0.0001372269,0.00003899673,0.001225005],"study_design_scores_gemma":[0.00001284744,0.00007972159,0.02687098,0.000007839311,0.00001665747,0.0004507405,0.00005533181,0.002085931,0.9682351,0.0001059476,0.002072154,0.000006836252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954424,0.001466846,0.002210803,0.000050862,0.00002111357,0.00000859702,0.0002545291,0.00003938107,0.0005055012],"genre_scores_gemma":[0.9985613,0.0002234007,0.0004204348,0.00001889069,0.000002869238,0.000004083065,0.0001632687,0.000004873516,0.0006008326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009541806,"threshold_uncertainty_score":0.003192067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01535697648889114,"score_gpt":0.2546300669586,"score_spread":0.2392730904697089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}