{"id":"W3147838034","doi":"10.1016/j.jtct.2021.03.033","title":"National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IIa. The 2020 Clinical Implementation and Early Diagnosis Working Group Report","year":2021,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"British Columbia Children's Hospital; CancerCare Manitoba; University of Manitoba","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute; AbbVie; University at Buffalo; Janssen Pharmaceuticals; Memorial Sloan-Kettering Cancer Center; American Society for Transplantation and Cellular Therapy; National Institutes of Health; Alvin J. Siteman Cancer Center; Universidad de Sevilla; Anthony Nolan; Huntsman Cancer Institute; Takeda Pharmaceuticals U.S.A.; University of Minnesota; Massachusetts General Hospital; Novartis; Celgene; Universität Hamburg; Bristol-Myers Squibb; AstraZeneca; CareDx; Government of South Australia; Dana-Farber Cancer Institute; Pfizer; Amgen; U.S. Department of Veterans Affairs","keywords":"Medicine; Clinical trial; Intensive care medicine; Disease; Standardization; Graft-versus-host disease; Clinical Practice; Consensus conference; MEDLINE; Chronic disease; Pathology; Physical therapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007088631,0.0001612691,0.0006098811,0.00008714008,0.0001256993,0.00003131519,0.0000395607,0.00008813231,0.00002572039],"category_scores_gemma":[0.0001847929,0.0001246058,0.0001425897,0.0001615432,0.0001117493,0.0000421695,0.000003884809,0.0001433642,5.922684e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006210396,"about_ca_system_score_gemma":0.001063572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003784924,"about_ca_topic_score_gemma":0.0001252272,"domain_scores_codex":[0.9959751,0.001140573,0.001969557,0.0003972557,0.0003426355,0.0001748409],"domain_scores_gemma":[0.9964864,0.002721028,0.0004590643,0.0001241421,0.0001138099,0.00009556729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02182084,0.001442409,0.7281646,0.003276748,0.001131334,0.0006411547,0.01134434,0.000007404871,0.006535163,0.001962313,0.000745095,0.2229286],"study_design_scores_gemma":[0.02857203,0.001235305,0.9469835,0.00112543,0.0002596545,0.00008684525,0.0008565295,0.0001154954,0.0106311,0.0000821936,0.009786647,0.000265336],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891837,0.003897221,0.002373867,0.002041951,0.0003962171,0.001992645,0.0000579563,0.00001880228,0.00003763175],"genre_scores_gemma":[0.9680322,0.02841015,0.001839945,0.0003282878,0.0001818552,0.0002743137,0.0009018867,0.00001833845,0.00001301795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2226633,"threshold_uncertainty_score":0.5081276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3148686311107944,"score_gpt":0.5038273522807666,"score_spread":0.1889587211699722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}