{"id":"W3148329018","doi":"10.12688/wellcomeopenres.13893.1","title":"Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism","year":2018,"lang":"en","type":"preprint","venue":"Wellcome Open Research","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Biotechnology and Biological Sciences Research Council; Chief Scientist Office, Scottish Government Health and Social Care Directorate; University of Edinburgh; Dr Mortimer and Theresa Sackler Foundation; Scottish Government; Scottish Funding Council; Wellcome Trust; Medical Research Council; Directorate for Biological Sciences; Centre for Cognitive Ageing and Cognitive Epidemiology; Wellcome","keywords":"Neuroticism; Heritability; Biology; Genetics; Psychology; Personality","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006850058,0.0003201081,0.0002168929,0.0006521154,0.0003500833,0.0003937124,0.0002713838,0.0002439414,0.00342787],"category_scores_gemma":[0.002773295,0.0001899967,0.0005870409,0.0007905287,0.0003049838,0.0001489454,0.000700607,0.0002851624,0.0001914612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000269602,"about_ca_system_score_gemma":0.000355038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01650779,"about_ca_topic_score_gemma":0.01897823,"domain_scores_codex":[0.9994199,0.0002588014,0.00006021949,0.00008917331,0.00008940407,0.00008259454],"domain_scores_gemma":[0.9982882,0.0004681055,0.0006967376,0.0001874552,0.0001069967,0.0002524367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00010973,0.0000176224,0.9970453,0.000007737109,0.00009512483,0.0001672827,0.0001279418,0.0001208057,0.0005087705,0.00004807634,0.00009396479,0.001657589],"study_design_scores_gemma":[0.000002971553,0.0000188772,0.9995684,0.00000267787,0.00001448072,0.00009376597,0.00003751306,0.000146168,0.0000264982,0.00003421364,0.00005268751,0.000001669666],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991388,0.00004506534,0.0001416061,0.00004077201,0.000002131418,0.000004869661,0.0003423005,0.000002669069,0.0002816858],"genre_scores_gemma":[0.9993179,0.00003211694,0.0001767003,0.000009423452,0.000004179155,0.000008036297,0.0003425373,0.000001607173,0.000107421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01650779,"threshold_uncertainty_score":0.03282344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05019788402945457,"score_gpt":0.3402223730683351,"score_spread":0.2900244890388806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}