{"id":"W3149398974","doi":"10.1111/jth.15338","title":"CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models","year":2021,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Blood Services; University of British Columbia","funders":"Institute of Circulatory and Respiratory Health; Center for Scientific Review; Heart and Stroke Foundation of Canada; Canada Excellence Research Chairs, Government of Canada; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Tissue factor; Thromboplastin; Coagulation; Thrombus; Tissue factor pathway inhibitor; Chemistry; Thrombosis; Prothrombinase; Partial thromboplastin time; Cell biology; Pathology; Biology; Thrombin; Immunology; Medicine; Internal medicine; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004296561,0.001056622,0.0004941077,0.001308886,0.0003371565,0.000790867,0.0005287908,0.001074704,0.003826493],"category_scores_gemma":[0.000309564,0.0003367038,0.0006299927,0.0004080186,0.0006552085,0.0004804007,0.0002448999,0.002136974,0.0009634551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003958238,"about_ca_system_score_gemma":0.0003160278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004676083,"about_ca_topic_score_gemma":0.0005974654,"domain_scores_codex":[0.9995522,0.0001025786,0.00004197271,0.00008841903,0.0001059892,0.000108895],"domain_scores_gemma":[0.99953,0.00005840456,0.0001494836,0.00005814608,0.00002767991,0.0001762811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002955066,0.0008485526,0.0004276463,0.0001248249,0.00004050454,0.0006690254,0.00004228468,0.0004177369,0.9886637,0.0008894986,0.000580113,0.004341058],"study_design_scores_gemma":[0.0009656782,0.006590323,0.004560456,0.00004669436,0.0002372317,0.002015414,0.0001644703,0.003468151,0.9736213,0.0005700513,0.007729103,0.00003117247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901162,0.001581775,0.003828725,0.0006017238,0.0001826945,0.0001035408,0.0008645298,0.0002951017,0.002425641],"genre_scores_gemma":[0.9861019,0.001794909,0.003146713,0.0001871164,0.00009144806,0.0002029456,0.0009372214,0.00006646602,0.007471233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003826493,"threshold_uncertainty_score":0.01280093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07270740624004274,"score_gpt":0.3206512155825124,"score_spread":0.2479438093424696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}