{"id":"W3149406154","doi":"10.1002/bit.27785","title":"Bioreactor production of rVSV‐based vectors in Vero cell suspension cultures","year":2021,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Western University; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Bioreactor; Vero cell; Suspension culture; Suspension (topology); Cell culture; Biology; Chemistry; Microbiology; Virology; Botany; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014964,0.0001070467,0.0001209723,0.0001288749,0.00002353509,0.000004737529,0.00008128792,0.0003166585,0.000005932214],"category_scores_gemma":[0.00005191342,0.0001013042,0.0000322304,0.0002386541,0.00009164276,0.00000274594,0.00006432395,0.0001391427,0.000001030345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197697,"about_ca_system_score_gemma":0.00004534901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007233428,"about_ca_topic_score_gemma":0.00008728317,"domain_scores_codex":[0.999325,0.00002364618,0.0001288614,0.0002819683,0.00006365663,0.0001768793],"domain_scores_gemma":[0.9996532,0.000005767274,0.0000292681,0.0002419434,0.00004287856,0.00002695432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001557195,0.0000558855,0.001031367,0.00004398464,0.0000131259,0.000008260206,0.00001015402,0.0002481297,0.9967111,0.00001270014,0.00004281239,0.001666808],"study_design_scores_gemma":[0.000331201,0.0004437243,0.0007121385,0.00002128365,0.000004765652,0.000008912384,0.00004860979,0.0001605072,0.9964911,0.000005308408,0.001665254,0.000107198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962724,0.00277439,0.000215375,0.0004873859,0.0001140213,0.00009247543,0.000004007032,0.00002418363,0.00001576719],"genre_scores_gemma":[0.9985421,0.0006890696,0.0006042208,0.0000181201,0.00003944892,0.000006311785,0.00003512398,0.00001246656,0.00005316027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002269684,"threshold_uncertainty_score":0.4131064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008987334413662127,"score_gpt":0.246549786377485,"score_spread":0.2375624519638229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}