{"id":"W3149413846","doi":"10.1111/jdv.17278","title":"Impact of baricitinib in combination with topical steroids on atopic dermatitis symptoms, quality of life and functioning in adult patients with moderate‐to‐severe atopic dermatitis from the BREEZE‐AD7 Phase 3 randomized trial","year":2021,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"Cilag; LEO Pharma; Galderma; Incyte; Les Laboratories Pierre Fabre; Regeneron Pharmaceuticals; Sanofi; Eli Lilly and Company","keywords":"Medicine; Atopic dermatitis; Dermatology Life Quality Index; Placebo; Quality of life (healthcare); Eczema Area and Severity Index; Janus kinase inhibitor; Presenteeism; Internal medicine; Physical therapy; Dermatology; Absenteeism; Janus kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001420908,0.001258438,0.003381865,0.0003238055,0.0004126346,0.001108735,0.0008326553,0.001518107,0.005186383],"category_scores_gemma":[0.001277181,0.0005054484,0.002489881,0.0004303472,0.0006951394,0.0006130692,0.0003586566,0.002009002,0.0007087762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008609261,"about_ca_system_score_gemma":0.001093169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001542734,"about_ca_topic_score_gemma":0.003399178,"domain_scores_codex":[0.9994687,0.000280096,0.00004061236,0.00007669486,0.00004674392,0.00008710431],"domain_scores_gemma":[0.9992849,0.0001918886,0.0001879368,0.000043681,0.00006448029,0.0002271005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9881054,0.001404391,0.000867072,0.0005927427,0.001079031,0.00002944651,0.00002455215,0.0001736256,0.001179762,0.00002806501,0.0004465245,0.006069315],"study_design_scores_gemma":[0.9647388,0.03069879,0.003043587,0.00003533496,0.0007287763,0.00003832009,0.00001622683,0.0002408421,0.0001381007,0.00004142564,0.0002701082,0.000009629659],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989442,0.005648099,0.0001771252,0.0004534287,0.0002686664,0.001988487,0.000798476,0.00005138461,0.001172318],"genre_scores_gemma":[0.9918029,0.00215061,0.0004959311,0.0005475879,0.0002497213,0.00229498,0.001122998,0.000009976895,0.00132543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005186383,"threshold_uncertainty_score":0.01735014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579163501841914,"score_gpt":0.2885635648316334,"score_spread":0.2727719298132143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}