{"id":"W3149633952","doi":"10.1038/s41419-021-03611-0","title":"Development of a bispecific immune engager using a recombinant malaria protein","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Gangstedfonden; Kirsten og Freddy Johansens Fond; Aase og Ejnar Danielsens Fond; Danmarks Grundforskningsfond; National Research Foundation; Svend Andersen Fonden; Kræftens Bekæmpelse","keywords":"Recombinant DNA; Malaria; Immune system; Virology; Biology; Immunology; Cancer research; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006748889,0.0001172292,0.0001119062,0.00002416744,0.0001426112,0.00002251727,0.00005259341,0.00005498302,0.00007654276],"category_scores_gemma":[0.00005798692,0.0001079907,0.00007958474,0.00005511599,0.0000275901,0.000003418593,0.0001257891,0.00004639504,0.000002957803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007505388,"about_ca_system_score_gemma":0.0003799183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004881983,"about_ca_topic_score_gemma":0.00000122856,"domain_scores_codex":[0.9992377,0.00005320338,0.0001965304,0.0002744159,0.00007971462,0.0001584501],"domain_scores_gemma":[0.9993478,0.000003324064,0.00006607888,0.0002409623,0.0000725195,0.0002693077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001413846,0.0002577828,0.002123178,0.0001601227,0.0000197102,0.00002719543,0.00004011748,0.0000127559,0.9962454,0.00009990846,0.0001951988,0.0006771979],"study_design_scores_gemma":[0.0009623694,0.00006618962,0.01039401,0.0001084557,0.00004310402,0.000006022359,0.0001084839,0.0001119666,0.9757211,0.0002535933,0.01195929,0.000265373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931065,0.005409384,0.0006184425,0.00001403286,0.0001150996,0.000143846,0.00001437075,0.000006565615,0.000571775],"genre_scores_gemma":[0.9952518,0.0001310489,0.003390873,0.00005406868,0.00004657454,0.00002561129,0.00007896027,0.00001425053,0.001006867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0205243,"threshold_uncertainty_score":0.4403731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858106592142345,"score_gpt":0.2476087896966714,"score_spread":0.229027723775248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}