{"id":"W3149633952","doi":"10.1038/s41419-021-03611-0","title":"Development of a bispecific immune engager using a recombinant malaria protein","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Gangstedfonden; Kirsten og Freddy Johansens Fond; Aase og Ejnar Danielsens Fond; Danmarks Grundforskningsfond; National Research Foundation; Svend Andersen Fonden; Kræftens Bekæmpelse","keywords":"Recombinant DNA; Malaria; Immune system; Virology; Biology; Immunology; Cancer research; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002228668,0.0004690362,0.0002144998,0.0002284372,0.0001058961,0.0003688334,0.000324832,0.0004056246,0.0007569193],"category_scores_gemma":[0.0001176392,0.0001633259,0.0002854093,0.0001639917,0.0001961299,0.0002489423,0.0003352248,0.0008103217,0.0004321327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003914368,"about_ca_system_score_gemma":0.0001478911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002991953,"about_ca_topic_score_gemma":0.0003145498,"domain_scores_codex":[0.9998119,0.00002960143,0.00001882561,0.00004706302,0.00005502125,0.00003756832],"domain_scores_gemma":[0.9999115,0.00001019901,0.00003527589,0.00001062119,0.00001179036,0.00002048497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002584739,0.00002565862,0.00006571239,0.00001609769,0.000003920363,0.0000263463,0.00001055912,0.0001193008,0.998387,0.0001554227,0.0000177399,0.001146411],"study_design_scores_gemma":[0.00001164728,0.0003190197,0.0004559791,0.000002052029,0.00001117078,0.0001818103,0.000007767954,0.001279043,0.9955384,0.00002689685,0.002162452,0.000003761531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633672,0.0006099534,0.03312751,0.0001243381,0.00003009781,0.0001706911,0.000231137,0.0002343225,0.002104857],"genre_scores_gemma":[0.9753284,0.0004243353,0.02097873,0.0000798996,0.000009618931,0.00007493029,0.0004048181,0.00003752029,0.002661644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007569193,"threshold_uncertainty_score":0.002840102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858106592142345,"score_gpt":0.2476087896966714,"score_spread":0.229027723775248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}