{"id":"W3149842350","doi":"10.1016/j.nmd.2020.08.218","title":"DMD – ANIMAL MODELS & PRECLINICAL TREATMENT","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Duchenne muscular dystrophy; Exon skipping; Exon; Muscular dystrophy; Medicine; Sarcolemma; Mutation; mdx mouse; Biology; Genetics; Internal medicine; Gene; Myocyte; Alternative splicing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001340024,0.001206585,0.0008822872,0.001341005,0.0007260276,0.0009075679,0.001264123,0.002206279,0.01633532],"category_scores_gemma":[0.0004145163,0.0003471694,0.000681486,0.0004850562,0.001157033,0.0009451021,0.0008015815,0.002911661,0.006855115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006509548,"about_ca_system_score_gemma":0.0006161571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000475636,"about_ca_topic_score_gemma":0.0009654665,"domain_scores_codex":[0.9994977,0.0001169531,0.00004721345,0.00007891669,0.0001860559,0.0000731605],"domain_scores_gemma":[0.999651,0.00005641615,0.00007192335,0.00007272592,0.00004659055,0.0001013728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006040199,0.005396686,0.001076396,0.003809097,0.0001568507,0.001918023,0.0001760717,0.001670748,0.7957821,0.01988356,0.03872205,0.1253681],"study_design_scores_gemma":[0.001272216,0.01844476,0.007309188,0.001740669,0.0004876792,0.00605532,0.0002195497,0.00182648,0.4192027,0.009772177,0.533567,0.0001023142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4024504,0.1961218,0.1113446,0.02414437,0.008362079,0.007560302,0.03198603,0.006107172,0.2119233],"genre_scores_gemma":[0.4785368,0.1666343,0.08026392,0.007393708,0.002684066,0.009558835,0.02646259,0.0008051611,0.2276606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01633532,"threshold_uncertainty_score":0.05464703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04827543033413526,"score_gpt":0.2895238312636299,"score_spread":0.2412484009294946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}