{"id":"W3149842350","doi":"10.1016/j.nmd.2020.08.218","title":"DMD – ANIMAL MODELS & PRECLINICAL TREATMENT","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Duchenne muscular dystrophy; Exon skipping; Exon; Muscular dystrophy; Medicine; Sarcolemma; Mutation; mdx mouse; Biology; Genetics; Internal medicine; Gene; Myocyte; Alternative splicing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004928436,0.0002539539,0.0002199147,0.00002005799,0.0001032624,0.00001647588,0.0002395195,0.0001830282,0.00008260569],"category_scores_gemma":[0.00009829736,0.0002373701,0.0003091246,0.00009825548,0.000129871,0.000007696974,0.0001096521,0.0001155418,0.00008442526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005654686,"about_ca_system_score_gemma":0.00006233186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002312534,"about_ca_topic_score_gemma":0.00007645636,"domain_scores_codex":[0.9985179,0.0001351019,0.0002239848,0.0006743028,0.0001251964,0.000323476],"domain_scores_gemma":[0.9992761,0.00001766067,0.00005852317,0.0004179757,0.0000255914,0.0002041214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004348344,0.001825173,0.01077098,0.0001186328,0.0007712583,0.0000144929,0.0008996077,0.01892844,0.905293,0.001712775,0.01562599,0.03969127],"study_design_scores_gemma":[0.01040873,0.01660359,0.02219309,0.00001629584,0.0003264772,0.00001348005,0.0003033387,0.00677118,0.01545187,0.004526878,0.9212111,0.002174031],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890937,0.0009749545,0.002540997,0.00290302,0.0001106014,0.0003420483,0.00001803308,0.00006340566,0.003953249],"genre_scores_gemma":[0.9953108,0.001063174,0.0002641594,0.002767643,0.000177054,0.00004936616,0.0002044432,0.00004265216,0.0001206526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9055851,"threshold_uncertainty_score":0.967967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04827543033413526,"score_gpt":0.2895238312636299,"score_spread":0.2412484009294946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}