{"id":"W3149876840","doi":"10.1093/jnci/djp403","title":"Response: Re: Topoisomerase II Alpha and Responsiveness of Breast Cancer to Adjuvant Chemotherapy","year":2009,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Queen's University; University of Toronto; University of Calgary; University of British Columbia; Sunnybrook Health Science Centre; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; BC Cancer Agency","funders":"","keywords":"Topoisomerase; Breast cancer; Adjuvant; Oncology; Medicine; Internal medicine; Adjuvant chemotherapy; Chemotherapy; Alpha (finance); Cancer; Pharmacology; Biology; DNA; Surgery; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004245948,0.001465945,0.002826904,0.001297381,0.002073872,0.002706072,0.004556929,0.03474358,0.01146193],"category_scores_gemma":[0.02906214,0.0006802178,0.002708366,0.001003042,0.001882666,0.0030655,0.001581174,0.03474041,0.01510433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004439642,"about_ca_system_score_gemma":0.003463313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004608159,"about_ca_topic_score_gemma":0.004585539,"domain_scores_codex":[0.9972923,0.0007321281,0.0005105668,0.0004755488,0.0006333485,0.0003560417],"domain_scores_gemma":[0.9869677,0.005620301,0.0006155859,0.0005065205,0.004756104,0.001533769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001301323,0.00003301951,0.0007135421,0.0001176388,0.00002592517,0.0007612985,0.00004769719,0.0000501402,0.0001340289,0.0003388247,0.9929296,0.004718167],"study_design_scores_gemma":[0.0004005161,0.0002897365,0.005592108,0.001004658,0.000161398,0.004739278,0.000793332,0.0007375616,0.000755469,0.006463518,0.9788224,0.0002400186],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003912387,0.001044902,0.0001272141,0.9427075,0.05408983,0.00006306623,0.0003704619,0.0001115516,0.001094287],"genre_scores_gemma":[0.002114998,0.0009001548,0.0002483588,0.9422425,0.05012465,0.0001009299,0.0001757588,0.00004849174,0.004044175],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03474358,"threshold_uncertainty_score":0.03834403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05730616838911928,"score_gpt":0.4214805945696888,"score_spread":0.3641744261805696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}