{"id":"W3151018740","doi":"","title":"Leveraging Metabolomics to Assess the Next Generation of Temozolomide-based Therapeutic Approaches for Glioblastomas","year":2013,"lang":"en","type":"article","venue":"","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Temozolomide; Glioblastoma; Medicine; Radiation therapy; Oncology; Chemotherapy; Dacarbazine; Malignancy; Internal medicine; Bioinformatics; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001029862,0.0006100659,0.0009089733,0.001309308,0.000232232,0.001148794,0.0002856026,0.0007352504,0.001139757],"category_scores_gemma":[0.0008575733,0.0003039559,0.0005638562,0.0007977004,0.000280039,0.001148661,0.0005870927,0.000789653,0.0003877695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006836819,"about_ca_system_score_gemma":0.0006725739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296777,"about_ca_topic_score_gemma":0.002552695,"domain_scores_codex":[0.9997516,0.00007978676,0.00001622736,0.00004029745,0.00007841394,0.00003368886],"domain_scores_gemma":[0.9997934,0.00004525599,0.00004725802,0.00001395453,0.00007115728,0.00002894249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001093922,0.0002334162,0.01432124,0.001204098,0.0003484836,0.0002820941,0.00007987371,0.002763765,0.8292636,0.001597619,0.001750465,0.1470613],"study_design_scores_gemma":[0.0001327815,0.002759652,0.07273613,0.0002747914,0.0008776271,0.001269254,0.0003141648,0.02849499,0.8447596,0.005786741,0.04243129,0.0001628755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6380658,0.2063512,0.1237391,0.008125796,0.0007862954,0.0007637786,0.006140497,0.001557658,0.01447002],"genre_scores_gemma":[0.7717655,0.1065442,0.1119138,0.002362705,0.000353305,0.0003174857,0.002786124,0.0001093355,0.003847735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309308,"threshold_uncertainty_score":0.005446494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2761074252926136,"score_gpt":0.3115660828665019,"score_spread":0.03545865757388827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}