{"id":"W3151244334","doi":"10.2106/jbjs.oa.20.00057","title":"The Dose-Response Effect of the Mast Cell Stabilizer Ketotifen Fumarate on Posttraumatic Joint Contracture","year":2021,"lang":"en","type":"article","venue":"JBJS Open Access","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Alberta; Alberta Bone and Joint Health Institute; University of Calgary","funders":"","keywords":"Contracture; Joint Contracture; Medicine; Knee Joint; Surgery; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000361904,0.00031732,0.0003576381,0.0002859045,0.0001282229,0.0001934855,0.0002396996,0.0003230091,0.001122104],"category_scores_gemma":[0.0004780022,0.000187376,0.0003088226,0.0001436215,0.0003339269,0.0002077234,0.0001605005,0.000524178,0.00018137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001909537,"about_ca_system_score_gemma":0.0002036537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005161918,"about_ca_topic_score_gemma":0.001304983,"domain_scores_codex":[0.9997203,0.00006558826,0.00003698742,0.00003539571,0.00007139637,0.00007041977],"domain_scores_gemma":[0.9994389,0.0001354453,0.0002074125,0.00004715749,0.00006423378,0.0001067709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01755387,0.002898915,0.003224094,0.0002335458,0.00006984638,0.0001143473,0.0001207461,0.0002577126,0.9639851,0.00004363774,0.0001127878,0.0113854],"study_design_scores_gemma":[0.0008212525,0.1622916,0.05318463,0.00003311442,0.0002118993,0.0003588305,0.0002011893,0.00101911,0.7805323,0.00003937516,0.00128279,0.00002401251],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986118,0.0008565091,0.0001831098,0.00002402455,0.00001655652,0.00003438783,0.00004806035,0.00000803513,0.000217552],"genre_scores_gemma":[0.9977576,0.0008611779,0.000512625,0.00002972886,0.00001781804,0.00005274355,0.0001126197,0.000002448079,0.0006532267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122104,"threshold_uncertainty_score":0.003753841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479898930887589,"score_gpt":0.313396944441422,"score_spread":0.2885979551325461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}