{"id":"W3151261099","doi":"10.1038/s41388-021-01767-9","title":"CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma","year":2021,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Gene silencing; microRNA; Cold-shock domain; Argonaute; Untranslated region; Translation (biology); Cell biology; RNA-induced silencing complex; Cancer research; RNA interference; Messenger RNA; Computational biology; Genetics; RNA; Gene; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003005903,0.0003944406,0.000338614,0.0004207954,0.0003002111,0.0004550469,0.0003107867,0.0004670699,0.003083348],"category_scores_gemma":[0.0002465549,0.0002451852,0.0003408674,0.0002074989,0.0003852751,0.000232617,0.000274876,0.001612564,0.0007729226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005141954,"about_ca_system_score_gemma":0.0004349078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009351319,"about_ca_topic_score_gemma":0.001670921,"domain_scores_codex":[0.9996892,0.00005780577,0.00003118379,0.00006860025,0.00007949818,0.00007371701],"domain_scores_gemma":[0.9997873,0.00005017656,0.00003960184,0.00003573728,0.00002258083,0.000064771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001245629,0.00005041583,0.00006722749,0.00002025253,0.000004328576,0.00002603673,0.000009848707,0.00007937176,0.9986346,0.0001924557,0.00008318495,0.0007077284],"study_design_scores_gemma":[0.00001892488,0.0001291596,0.001234356,0.000002671524,0.000008244119,0.00007146229,0.00002637122,0.001263908,0.995047,0.00004487949,0.00215014,0.000002762775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885494,0.001101755,0.005132279,0.0004162946,0.0001824211,0.0000557305,0.0008614541,0.0002596039,0.003441065],"genre_scores_gemma":[0.992014,0.0003675681,0.001782357,0.00009777234,0.00001242295,0.00004800745,0.0006332401,0.00005079192,0.004993854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003083348,"threshold_uncertainty_score":0.01031482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0111635403392615,"score_gpt":0.2649189793352164,"score_spread":0.2537554389959549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}