{"id":"W3151261099","doi":"10.1038/s41388-021-01767-9","title":"CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma","year":2021,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Gene silencing; microRNA; Cold-shock domain; Argonaute; Untranslated region; Translation (biology); Cell biology; RNA-induced silencing complex; Cancer research; RNA interference; Messenger RNA; Computational biology; Genetics; RNA; Gene; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429982,0.00008151302,0.0001393827,0.00004298448,0.00002185563,0.000007777777,0.0001135719,0.00008887622,0.0000481128],"category_scores_gemma":[0.0002050269,0.00008058563,0.00005786997,0.0001561839,0.00003440844,0.000002009589,0.0001022112,0.00006790934,0.00001547948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001587088,"about_ca_system_score_gemma":0.0001650215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001369178,"about_ca_topic_score_gemma":0.000430194,"domain_scores_codex":[0.9991893,0.00005663023,0.0001849916,0.0002196224,0.0001104328,0.0002390395],"domain_scores_gemma":[0.9995461,0.00002103984,0.00004388952,0.0002237573,0.00009702625,0.00006825099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003230456,0.00004815531,0.01946053,0.00001831174,0.00002294265,0.00005386113,0.0000234434,0.00001705011,0.9778774,0.000004478913,0.0003184966,0.002122985],"study_design_scores_gemma":[0.0004818598,0.00009611758,0.00330445,0.00002605835,0.000003500265,0.00001835275,0.0001731146,0.00007363046,0.9936699,0.000009512379,0.002055574,0.00008788329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961954,0.002599261,0.00005587879,0.0001309744,0.00004013977,0.00005488651,0.00001845174,0.000003521294,0.0009014476],"genre_scores_gemma":[0.9975305,0.0004140118,0.0005624478,0.00009897524,0.00007092671,0.00000615278,0.000132963,0.00001282377,0.001171166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01615608,"threshold_uncertainty_score":0.3286187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0111635403392615,"score_gpt":0.2649189793352164,"score_spread":0.2537554389959549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}