{"id":"W3151328747","doi":"10.1099/mic.0.001041","title":"From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis","year":2021,"lang":"en","type":"review","venue":"Microbiology","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Phagosome; Tuberculosis; Mycobacterium tuberculosis; Intracellular; Biology; Obligate; Intracellular parasite; Pathogen; Human pathogen; Microbiology; Immunology; Medicine; Cell biology; Genetics; Gene; Ecology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003687313,0.000608073,0.0009481803,0.00183238,0.0002602187,0.001079181,0.0006416729,0.001129128,0.00485976],"category_scores_gemma":[0.0007790635,0.000170981,0.000397816,0.001443288,0.0003875428,0.001388588,0.0006794799,0.001801067,0.002649351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005145177,"about_ca_system_score_gemma":0.0009724828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006803753,"about_ca_topic_score_gemma":0.001072546,"domain_scores_codex":[0.9998347,0.00003439843,0.00002065633,0.00002685301,0.00006408675,0.00001928113],"domain_scores_gemma":[0.9997504,0.0001093609,0.00003301559,0.000007526777,0.00006966062,0.00002990234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006978269,0.00005609047,0.0001561459,0.02167546,0.00006740601,0.0002362024,0.0001074321,0.0002289789,0.002901078,0.005300832,0.05240707,0.9167936],"study_design_scores_gemma":[0.000006858168,0.00006824928,0.000352337,0.00315746,0.00004480779,0.0008869438,0.00004551805,0.00003666607,0.0003070168,0.001195099,0.9938902,0.000008907587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001020821,0.9975714,0.0001199305,0.0005141431,0.0003965879,0.000004366101,0.00002116735,0.00001026183,0.001259956],"genre_scores_gemma":[0.0006879233,0.9975665,0.0001542901,0.0003783705,0.0003176766,0.000005409259,0.0000311639,0.000002226876,0.0008566387],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00485976,"threshold_uncertainty_score":0.01625746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03957297014326887,"score_gpt":0.3486398586169915,"score_spread":0.3090668884737226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}