{"id":"W3151335737","doi":"10.1002/ajh.26181","title":"Ineffectiveness of high‐dose methotrexate for prevention of <scp>CNS</scp> relapse in diffuse large <scp>B</scp>‐cell lymphoma","year":2021,"lang":"en","type":"article","venue":"American Journal of Hematology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Health; Alberta Health Services; University of Calgary; Alberta Advanced Education; Alberta Cancer Foundation; University of Alberta","funders":"","keywords":"Medicine; Methotrexate; Internal medicine; Lymphoma; Diffuse large B-cell lymphoma; Primary central nervous system lymphoma; Central nervous system; Gastroenterology; Antifolate; Chemotherapy; Oncology; Antimetabolite","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006468216,0.0001209972,0.0002641852,0.0002797649,0.0001913198,0.0003684888,0.0003044312,0.0001857055,0.0003252839],"category_scores_gemma":[0.001899852,0.0000831355,0.0001950613,0.0004049844,0.0002649179,0.0001682562,0.0001307299,0.0002808277,0.0000628672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001470298,"about_ca_system_score_gemma":0.001503698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03016998,"about_ca_topic_score_gemma":0.08306206,"domain_scores_codex":[0.9996721,0.0001060126,0.00003375368,0.00003234086,0.0001103581,0.00004550452],"domain_scores_gemma":[0.9987423,0.0002610987,0.0005882907,0.00006181932,0.0001454828,0.0002010765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001388508,0.0001817783,0.9680793,0.00006330516,0.00007559033,0.0003147814,0.0001016131,0.0002078377,0.002083575,0.00001517902,0.0001722673,0.02731637],"study_design_scores_gemma":[0.0000411695,0.001059498,0.9973589,0.0000164317,0.00005761517,0.0004786724,0.00005495995,0.0002128662,0.0004108476,0.000008171592,0.0002979861,0.000003006533],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981793,0.001278324,0.0000345045,0.0000504608,0.000003945763,0.00001047833,0.0000338388,0.000004393663,0.0004048642],"genre_scores_gemma":[0.9995894,0.0002512003,0.00004456915,0.00002107861,0.000006426603,0.000001608538,0.00004084637,7.472482e-7,0.0000441088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03016998,"threshold_uncertainty_score":0.0599888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117595148440877,"score_gpt":0.2873974435163136,"score_spread":0.2762214920319048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}