{"id":"W3151575369","doi":"10.1523/eneuro.0053-21.2021","title":"Retinal Pigment Epithelium and Neural Retinal Progenitors Interact via Semaphorin 6D to Facilitate Optic Cup Morphogenesis","year":2021,"lang":"en","type":"article","venue":"eNeuro","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Government of Canada; University of Calgary","keywords":"Morphogenesis; Biology; Retina; Zebrafish; Cell biology; Retinal pigment epithelium; Embryonic stem cell; Optic cup (embryology); Retinal; Cell migration; Neuroscience; Cell; Eye development; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618361,0.0002360285,0.0001711409,0.00005179878,0.00009447987,0.00005541598,0.0001465498,0.000070296,0.000076768],"category_scores_gemma":[0.0001907014,0.0002312649,0.00009331923,0.0001380703,0.00005125026,0.000006261482,0.0002568284,0.00009515132,0.00003275531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001764722,"about_ca_system_score_gemma":0.0000738634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001772401,"about_ca_topic_score_gemma":0.00001650281,"domain_scores_codex":[0.9984745,0.0001143826,0.0002564691,0.0005813985,0.0002359364,0.0003372575],"domain_scores_gemma":[0.9993189,0.00002034129,0.00005251919,0.00028146,0.0001348729,0.0001919096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000359222,0.00007981172,0.01414835,0.00005242796,0.00005445754,0.0002402916,0.0002441928,0.00006544399,0.9735566,0.00001068645,0.002675647,0.008512829],"study_design_scores_gemma":[0.0007518717,0.0008365532,0.04169787,0.00003599517,0.00004964823,0.0005973139,0.0003292103,0.0001713421,0.8828706,0.00004983068,0.0719343,0.0006754411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965747,0.0006319135,0.0004768532,0.0008715176,0.0003367048,0.0001988861,0.00001398329,0.00001854793,0.0008769149],"genre_scores_gemma":[0.9953756,0.0001378776,0.001717026,0.0005272279,0.0001258891,0.00004362868,0.00007754644,0.00002910492,0.001966039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09068602,"threshold_uncertainty_score":0.9430711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541112325814105,"score_gpt":0.2334233733032158,"score_spread":0.2180122500450747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}