{"id":"W3151575369","doi":"10.1523/eneuro.0053-21.2021","title":"Retinal Pigment Epithelium and Neural Retinal Progenitors Interact via Semaphorin 6D to Facilitate Optic Cup Morphogenesis","year":2021,"lang":"en","type":"article","venue":"eNeuro","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Government of Canada; University of Calgary","keywords":"Morphogenesis; Biology; Retina; Zebrafish; Cell biology; Retinal pigment epithelium; Embryonic stem cell; Optic cup (embryology); Retinal; Cell migration; Neuroscience; Cell; Eye development; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008090034,0.0001908587,0.0001405527,0.0002008174,0.0001893823,0.0003019946,0.0001471026,0.0002160221,0.0007258115],"category_scores_gemma":[0.0001188631,0.0001638823,0.0001319039,0.00007678135,0.0001378975,0.0001757662,0.0006939211,0.0002727144,0.0002917929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872065,"about_ca_system_score_gemma":0.0002628295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005474798,"about_ca_topic_score_gemma":0.001481119,"domain_scores_codex":[0.9998672,0.00002184176,0.000007191309,0.00001590379,0.00005477335,0.00003309321],"domain_scores_gemma":[0.9999516,0.000005643621,0.00001467454,0.00000328602,0.000005253615,0.00001951865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002294713,0.000004035622,0.0006182741,0.00001561219,0.000001803003,0.0001458783,0.00001822381,0.00005046748,0.9974102,0.0003470725,0.00003580001,0.001329727],"study_design_scores_gemma":[0.00001316681,0.00009837034,0.03187725,0.00001141383,0.00001119495,0.001313592,0.0001490964,0.001944936,0.9550307,0.0002815216,0.009263278,0.000005381936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908475,0.001112915,0.003236629,0.0001134007,0.00001814894,0.00001319559,0.00008264213,0.00004351141,0.004532099],"genre_scores_gemma":[0.9915131,0.0005304664,0.003061565,0.00004436168,0.000005005217,0.00001101645,0.00009928186,0.000008558512,0.004726774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007258115,"threshold_uncertainty_score":0.002428055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541112325814105,"score_gpt":0.2334233733032158,"score_spread":0.2180122500450747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}