{"id":"W3151802177","doi":"10.1016/j.jtos.2020.11.012","title":"Repurposing medications","year":2020,"lang":"en","type":"article","venue":"The Ocular Surface","topic":"Pharmaceutical Practices and Patient Outcomes","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Networks of Centres of Excellence of Canada; U.S. Food and Drug Administration","keywords":"Repurposing; Medicine; Drug repositioning; Intensive care medicine; Pharmacology; Drug; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004131912,0.0002266039,0.0003317448,0.0006339388,0.0004537237,0.0009994474,0.0003083172,0.000391596,0.02522884],"category_scores_gemma":[0.001834311,0.00005065582,0.0006422661,0.0007901724,0.000238336,0.0004460638,0.000549712,0.0008335527,0.004752472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003808698,"about_ca_system_score_gemma":0.0007924122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012022,"about_ca_topic_score_gemma":0.002059622,"domain_scores_codex":[0.9993097,0.000125582,0.00008901003,0.0000641951,0.0002967921,0.0001148379],"domain_scores_gemma":[0.9990323,0.0001458088,0.000385445,0.00009324391,0.0002200309,0.0001232332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005937587,0.0007055367,0.0317337,0.00135549,0.0002163479,0.001910693,0.0002753973,0.00005919327,0.008574381,0.003563359,0.03546485,0.9155472],"study_design_scores_gemma":[0.0004859629,0.003398784,0.1426639,0.002518812,0.0008031169,0.02017084,0.001380164,0.0003690114,0.02177028,0.004189834,0.8021958,0.00005355126],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3337073,0.1112967,0.004120597,0.01506136,0.001741143,0.0009145741,0.00296822,0.0005487709,0.5296412],"genre_scores_gemma":[0.8431551,0.04715117,0.006860812,0.01232315,0.002104102,0.000352393,0.002963303,0.00008369981,0.0850061],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02522884,"threshold_uncertainty_score":0.08439887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1552342397731835,"score_gpt":0.3932314399986392,"score_spread":0.2379972002254557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}