{"id":"W3152297100","doi":"10.1093/jnci/djv384","title":"RE: Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome","year":2015,"lang":"en","type":"letter","venue":"JNCI Journal of the National Cancer Institute","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"","keywords":"Aspirin; Colorectal cancer; Medicine; Ibuprofen; Lynch syndrome; Internal medicine; Oncology; Cancer; Pharmacology; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001665963,0.0008270788,0.001759539,0.0008891925,0.002432525,0.001798789,0.001298607,0.02483346,0.006481086],"category_scores_gemma":[0.01741466,0.0007169631,0.000912538,0.0006486353,0.001002184,0.001946204,0.0006836525,0.02063289,0.004510444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00243691,"about_ca_system_score_gemma":0.002858499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01236029,"about_ca_topic_score_gemma":0.02040436,"domain_scores_codex":[0.9987895,0.0003689585,0.0002130905,0.0001604822,0.0003485592,0.0001194558],"domain_scores_gemma":[0.9945951,0.00288205,0.0004569367,0.0001746669,0.0009123278,0.0009788498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002972573,0.0001340599,0.008254834,0.00010896,0.00007461203,0.002988534,0.0001400985,0.00009826168,0.0002894418,0.001170299,0.9721876,0.01425599],"study_design_scores_gemma":[0.001181422,0.0005402969,0.02756785,0.002169018,0.0005149654,0.01392274,0.001222047,0.002783861,0.000913544,0.009608612,0.9393365,0.0002390987],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001424219,0.003149182,0.00005251556,0.9685269,0.02288965,0.00001226341,0.0001443189,0.00003151413,0.003769431],"genre_scores_gemma":[0.01757264,0.00318503,0.0001928654,0.837633,0.130435,0.00004826557,0.0001264216,0.00002909178,0.01077772],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02483346,"threshold_uncertainty_score":0.02457672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05558847230403469,"score_gpt":0.3452287094254036,"score_spread":0.2896402371213689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}