{"id":"W3152340772","doi":"10.1161/circoutcomes.120.006646","title":"Lipid Testing, Lipid-Modifying Therapy, and PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Eligibility in 27 979 Patients With Incident Acute Coronary Syndrome","year":2021,"lang":"en","type":"article","venue":"Circulation Cardiovascular Quality and Outcomes","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian VIGOUR Centre; University of Alberta Hospital; St. Michael's Hospital","funders":"","keywords":"Medicine; PCSK9; Acute coronary syndrome; Evolocumab; Internal medicine; Statin; Population; Unstable angina; Cohort; Lipoprotein; Gastroenterology; Cholesterol; Myocardial infarction; LDL receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00249292,0.0004190948,0.001499092,0.0001587323,0.0002175328,0.00009427046,0.00008025832,0.0002655956,0.00002898728],"category_scores_gemma":[0.0006810802,0.0003463411,0.0005524444,0.000534058,0.0001743038,0.0003035086,0.0001253051,0.0004211658,0.000007130759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002273384,"about_ca_system_score_gemma":0.0003731177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001236169,"about_ca_topic_score_gemma":0.00009247924,"domain_scores_codex":[0.9956887,0.000790231,0.0008149508,0.001005564,0.00124791,0.0004526497],"domain_scores_gemma":[0.9974683,0.0001661967,0.0001839226,0.001228048,0.0006306823,0.0003228823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002554434,0.0002340695,0.966406,0.0005699137,0.001677581,0.0002722762,0.000328851,0.00007543421,0.0001562554,0.00004422447,0.000004873494,0.02997508],"study_design_scores_gemma":[0.00759371,0.0002231852,0.9894611,0.0002345767,0.0004428899,0.0003835002,0.0001774026,0.00008079229,0.0003174693,0.00006809419,0.0005930425,0.0004241853],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892441,0.007893115,0.0003098569,0.0003416316,0.0002864972,0.001761449,0.00003102364,0.00008866013,0.00004368],"genre_scores_gemma":[0.997658,0.000477569,0.000782232,0.0006326512,0.0001129693,0.0000563538,0.0002008994,0.00005099586,0.00002834075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0295509,"threshold_uncertainty_score":0.9998989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05209750510048519,"score_gpt":0.3079381120838482,"score_spread":0.255840606983363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}