{"id":"W3152509858","doi":"10.1101/2021.04.13.439667","title":"A Platform for Oncogenomic Reporting and Interpretation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre; Pancreas Centre (Canada); University of British Columbia","funders":"Common Fund; NIH Office of the Director; National Human Genome Research Institute; National Cancer Institute; BC Cancer Foundation; National Institutes of Health; Canada Research Chairs; Genome British Columbia; Genome Canada","keywords":"Interpretation (philosophy); Computer science; Data science; Matching (statistics); Graph; Limiting; Medicine; Engineering; Pathology; Theoretical computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02196072,0.002187032,0.001171092,0.008707992,0.001114874,0.008469207,0.003932638,0.001566636,0.01322982],"category_scores_gemma":[0.0442881,0.00144116,0.001295053,0.005839069,0.001407404,0.005499726,0.007580602,0.003645096,0.01087726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001943849,"about_ca_system_score_gemma":0.004256439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002460881,"about_ca_topic_score_gemma":0.001319427,"domain_scores_codex":[0.989648,0.002277962,0.001327596,0.002119769,0.004250342,0.0003764178],"domain_scores_gemma":[0.9578986,0.0127623,0.004583032,0.01634391,0.007032082,0.001380109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001177648,0.0003339622,0.01146911,0.001351938,0.0004785809,0.001985523,0.001437792,0.01219429,0.0335228,0.08982606,0.4007817,0.4454406],"study_design_scores_gemma":[0.0002520036,0.0001421316,0.007279671,0.0005491461,0.0002030742,0.001500283,0.0004726753,0.1292713,0.09762698,0.1743868,0.5877962,0.0005197966],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"software","genre_scores_codex":[0.003989144,0.0003685423,0.7594025,0.00199512,0.0003222957,0.0007483927,0.03205221,0.1910131,0.01010872],"genre_scores_gemma":[0.0590991,0.000611877,0.8300884,0.001130361,0.000359468,0.00126975,0.08161763,0.01912238,0.006700953],"genre_candidate":"software","genre_consensus":null,"teacher_disagreement_score":0.02196072,"threshold_uncertainty_score":0.1161408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523324458812478,"score_gpt":0.2435866024659434,"score_spread":0.2283533578778186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}