{"id":"W3152587167","doi":"10.1101/2021.04.08.21255115","title":"Program and patient characteristics for the United States Expanded Access Program to COVID-19 convalescent plasma","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute on Aging; National Institute of Allergy and Infectious Diseases; Mayo Clinic; Natural Sciences and Engineering Research Council of Canada; Biomedical Advanced Research and Development Authority; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Takeda Oncology; U.S. Department of Health and Human Services","keywords":"Expanded access; Medicine; Coronavirus disease 2019 (COVID-19); Pandemic; Ethnic group; Convalescent plasma; Clinical trial; Referral; Family medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Emergency medicine; Internal medicine; Disease; Political science; Infectious disease (medical specialty)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009146933,0.0002240288,0.0002169702,0.0009059048,0.001084877,0.0007170276,0.0005851307,0.0005160612,0.01813501],"category_scores_gemma":[0.003826682,0.0001504259,0.0003472122,0.001280288,0.0001827293,0.0006034815,0.0006850117,0.001292343,0.002152712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001043743,"about_ca_system_score_gemma":0.003155552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01020008,"about_ca_topic_score_gemma":0.01870621,"domain_scores_codex":[0.999059,0.0001600348,0.00009746238,0.0001847577,0.0002468474,0.0002518618],"domain_scores_gemma":[0.9961054,0.0003572232,0.001375678,0.0001865655,0.000647881,0.001327283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008873292,0.001384329,0.9435695,0.00007211699,0.00005420737,0.000191749,0.0001522004,0.0003570677,0.0003528783,0.0003884755,0.03414045,0.01844961],"study_design_scores_gemma":[0.0001932045,0.0007216641,0.9807036,0.00005627051,0.00002741613,0.0004109163,0.0003870011,0.0006173748,0.0001263801,0.000157497,0.01658145,0.00001725691],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8944536,0.0005429723,0.002080517,0.004164427,0.0001917659,0.002903669,0.05680566,0.0003205288,0.03853693],"genre_scores_gemma":[0.9359217,0.0003887701,0.003440135,0.00347978,0.0002555142,0.005885021,0.03751064,0.00009917084,0.01301931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01813501,"threshold_uncertainty_score":0.06066763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1404432444013448,"score_gpt":0.4882507825351768,"score_spread":0.3478075381338321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}