{"id":"W3152609813","doi":"10.1097/01.hjh.0000747440.12540.5c","title":"MIR-338-3P DOWN-REGULATION IN SMALL ARTERIES OF HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE MAY ACT VIA UP-REGULATION OF ALKALINE CERAMIDASE 2 AND GLUTATHIONE PEROXIDASE 3","year":2021,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Aortic Thrombus and Embolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; McGill University","funders":"","keywords":"microRNA; Medicine; Kidney disease; Messenger RNA; RNA; Fold change; Internal medicine; Gene silencing; Kidney; Endothelial dysfunction; Gene expression; Endocrinology; Bioinformatics; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001734295,0.0002026756,0.0003214807,0.0002488386,0.0001548184,0.0002425316,0.00008967421,0.000176349,0.002544088],"category_scores_gemma":[0.000350611,0.0001334533,0.000294945,0.0001876601,0.0001081831,0.00008859822,0.0001150668,0.0003209362,0.0003003047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001002005,"about_ca_system_score_gemma":0.0001250341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004730555,"about_ca_topic_score_gemma":0.0006894535,"domain_scores_codex":[0.9998665,0.00002481578,0.00001283931,0.00004138152,0.00003531332,0.00001915597],"domain_scores_gemma":[0.99985,0.00004186395,0.0000559206,0.000008015372,0.00001951669,0.00002457248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005454297,0.0002074467,0.1200023,0.0002699378,0.0002245467,0.001182255,0.00028246,0.0001390044,0.8512898,0.0001648785,0.0006885208,0.02009457],"study_design_scores_gemma":[0.0001123264,0.0007012223,0.9332146,0.00002357934,0.0002495047,0.001741947,0.0001211954,0.001179855,0.06015278,0.0001396322,0.002351126,0.00001231821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953159,0.001067873,0.001602485,0.0001131726,0.00004463779,0.00001829914,0.0007566769,0.000052457,0.001028627],"genre_scores_gemma":[0.9966755,0.0003277704,0.001653657,0.0000677304,0.00002295352,0.0000358939,0.0003638637,0.00001266285,0.0008399778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002544088,"threshold_uncertainty_score":0.008510768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141718431066061,"score_gpt":0.2231426494451087,"score_spread":0.2089708063385026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}