{"id":"W3152609813","doi":"10.1097/01.hjh.0000747440.12540.5c","title":"MIR-338-3P DOWN-REGULATION IN SMALL ARTERIES OF HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE MAY ACT VIA UP-REGULATION OF ALKALINE CERAMIDASE 2 AND GLUTATHIONE PEROXIDASE 3","year":2021,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Aortic Thrombus and Embolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; McGill University","funders":"","keywords":"microRNA; Medicine; Kidney disease; Messenger RNA; RNA; Fold change; Internal medicine; Gene silencing; Kidney; Endothelial dysfunction; Gene expression; Endocrinology; Bioinformatics; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001720614,0.0001971699,0.0007537241,0.00019007,0.00004838152,0.0000105999,0.00004430792,0.00009612631,0.00009813274],"category_scores_gemma":[0.0003213147,0.0001387611,0.0001200815,0.0002388954,0.0001444502,0.0002379281,0.00003974697,0.0001866379,0.000001359148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008440228,"about_ca_system_score_gemma":0.0003889971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004956016,"about_ca_topic_score_gemma":0.00002110206,"domain_scores_codex":[0.998321,0.00008399566,0.00077471,0.0002077171,0.0004212355,0.0001913327],"domain_scores_gemma":[0.9973501,0.00006124182,0.0005973473,0.0002441378,0.001432006,0.0003151728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006954517,0.00173926,0.1019881,0.0008190108,0.0002747207,0.0005717226,0.000979872,0.0005649927,0.8724191,0.00007461666,0.0007338872,0.01288022],"study_design_scores_gemma":[0.009227742,0.001049745,0.9653901,0.001607006,0.0005529234,0.0004267397,0.0001522556,0.00386888,0.01710012,0.0002565488,0.0002039484,0.0001640187],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967819,0.0007581,0.0004665916,0.001537604,0.0001890112,0.000232045,0.00001923102,0.000006105176,0.000009342913],"genre_scores_gemma":[0.9979925,0.0001420194,0.001189735,0.0003477051,0.0001308972,0.000001387913,0.0001123679,0.00002462801,0.00005882856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8634019,"threshold_uncertainty_score":0.5658513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141718431066061,"score_gpt":0.2231426494451087,"score_spread":0.2089708063385026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}