{"id":"W3152848291","doi":"10.1186/s13104-021-05663-z","title":"A novel blood-based assay for treatment monitoring of tuberculosis","year":2021,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; Ministerie van Buitenlandse Zaken; Australian Government; Department for International Development; National Institutes of Health; U.S. Department of Defense; Department for International Development, UK Government; Department of Foreign Affairs and Trade, Australian Government; Bill and Melinda Gates Foundation; Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie; Universidad Peruana Cayetano Heredia; Dr. Ralph and Marian Falk Medical Research Trust","keywords":"GeneXpert MTB/RIF; Medicine; Tuberculosis; Internal medicine; Tb treatment; Gene signature; Prospective cohort study; Sputum; Gene; Gene expression; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001417634,0.000511506,0.0005943743,0.001216725,0.0001859624,0.0006210766,0.0005167609,0.0009551962,0.001378864],"category_scores_gemma":[0.002355568,0.0001620046,0.0003512035,0.0008147834,0.0003527218,0.000272221,0.0003040808,0.0006689171,0.0006710479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004044996,"about_ca_system_score_gemma":0.0004004162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005642718,"about_ca_topic_score_gemma":0.0008198426,"domain_scores_codex":[0.997315,0.0008300549,0.0001242135,0.0005096329,0.001083808,0.0001373322],"domain_scores_gemma":[0.9986776,0.0003995037,0.0003733474,0.0001059851,0.0003235927,0.0001200362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002068502,0.0004326801,0.2065121,0.0004172919,0.0001559545,0.0001647503,0.0001740114,0.0008183763,0.6812097,0.0002731374,0.001775178,0.1059985],"study_design_scores_gemma":[0.0002411153,0.006055374,0.4768851,0.0001641968,0.0003338627,0.004213706,0.000200727,0.01748001,0.482491,0.0005659378,0.0112653,0.0001035596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8804581,0.009738106,0.09553221,0.0007095973,0.0004346599,0.0006307949,0.005946776,0.001770069,0.00477985],"genre_scores_gemma":[0.9351719,0.0008167264,0.05820183,0.0007340646,0.0001690007,0.0003756576,0.0022759,0.00004193658,0.002212849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417634,"threshold_uncertainty_score":0.007497251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2913481744011678,"score_gpt":0.4755042175429726,"score_spread":0.1841560431418048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}